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Anticancer effects of garlic and garlic-derived compounds for breast cancer control.
Anticancer Agents Med Chem. 2011 Mar 1;11(3):249-53
Authors: Tsubura A, Lai YC, Kuwata M, Uehara N, Yoshizawa K
Garlic and garlic-derived compounds reduce the development of mammary cancer in animals and suppress the growth of human breast cancer cells in culture. Oil-soluble compounds derived from garlic, such as diallyl disulfide (DADS), are more effective than water-soluble compounds in suppressing breast cancer. Mechanisms of action include the activation of metabolizing enzymes that detoxify carcinogens, the suppression of DNA adduct formation, the inhibition of the production of reactive oxygen species, the regulation of cell-cycle arrest and the induction of apoptosis. Selenium-enriched garlic or organoselenium compounds provide more potent protection against mammary carcinogenesis in rats and greater inhibition of breast cancer cells in culture than natural garlic or the respective organosulfur analogues. DADS synergizes the effect of eicosapentaenoic acid, a breast cancer suppressor, and antagonizes the effect of linoleic acid, a breast cancer enhancer. Moreover, garlic extract reduces the side effects caused by anti-cancer agents. Thus, garlic and garlic-derived compounds are promising candidates for breast cancer control.—PMID: 21269259 [PubMed – indexed for MEDLINE]
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Modulation of histone acetylation by garlic sulfur compounds.
Anticancer Agents Med Chem. 2011 Mar 1;11(3):254-9
Authors: Druesne-Pecollo N, Latino-Martel P
Preclinical studies have shown that fresh garlic extracts, aged garlic, garlic oil and specific organosulfur compounds generated by processing garlic could alter carcinogen metabolism, inhibit tumor cell growth through induction of cell cycle arrest or apoptosis, or angiogenesis. In particular, recent studies have suggested that anticarcinogenic effects of certain garlic compounds may implicate at least in part a modulation of histone acetylation, a process involved in the regulation of gene expression, resulting from the inhibition of histone deacetylase activity. The aim of this review is to describe available data on sulfur compounds from garlic and histone acetylation and to discuss their potential for cancer prevention. Available data indicate that garlic compounds could inhibit histone deacetylase activity and induce histone hyperacetylation in vitro as well as in vivo. Sparse studies provide evidence of an involvement of histone acetylation in modulation of gene expression by diallyl disulfide and allyl mercaptan. These effects were observed at high concentrations. Further investigations are needed to determine if the HDAC inhibitory effects of garlic organosulfur compounds might play a role in primary cancer prevention at doses achievable by human diet.–PMID: 21269249 [PubMed – indexed for MEDLINE]—Special Note— Acetylation is a reaction, usually with acetic acid, that introduces an acetyl radical into an organic compound—
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Chemical properties and mechanisms determining the anti-cancer action of garlic-derived organic sulfur compounds.
Anticancer Agents Med Chem. 2011 Mar 1;11(3):267-71
Authors: Cerella C, Dicato M, Jacob C, Diederich M
Organic sulfur compounds (OSCs) derived from plants, fungi or bacteria can serve as chemopreventive and/or chemotherapeutic agents and have been attracting medical and research interest as a promising source for novel anti-cancer agents. Garlic, which has long been used as a medicinal plant in different cultures due to its multiple beneficial effects, contains a consistent number of OSCs, the majority of which are currently under investigation for their biological activities. Experimental animal and laboratory studies have shown strong evidence that garlic OSCs may affect cancer cells by promoting early mitotic arrest followed by apoptotic cell death without affecting healthy cells. The ability of OSCs to hinder cancer cell proliferation and viability tightly correlates with the length of the sulfur chain. Current data support a mechanism of mitotic arrest of cancer cells due to the alteration of the microtubule network, possibly as a consequence of the high reactivity of sulfur atoms against the thiol groups of different cellular macromolecules controlling crucial regulatory functions. Taken together, these findings indicate a promising potential for the use of garlic-derived sulfur compounds in chemoprevention and chemotherapy.- PMID: 21269260 [PubMed – indexed for MEDLINE]
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Recipe For Garlic with Wine—Take a whole bulb of Garlic-Peeled and placed in blender or Manual Extractor ( wheat grass extractor) And add a 1 ¼- 1 ½ cup of white or red wine –Blend for 5-7 minutes then strain—add to GLASS container—utilize 1-3 tsp at a time—START OUT WITH 1 TSP—THIS IS POTENT—THIS will boost immune system—regulate cholesterol—fight cancer on several different levels—increase nitric oxide production—will have cycstein and resveratrol which respond to liver spleen-heart-lung-blood—and fats—may see improvement in hearing—will see more circulation ( add Vitamin B1 with this for those of you with Fibro or Restless leg syndrome or if diabetic) Increase immune response ( add 1-2 drops of lugols with this as well to boost the immune functions)
Recipe for Garlic and Vinegar– Take a whole bulb of Garlic-Peeled and placed in blender or Manual Extractor ( wheat grass extractor) And add a 1 ¼- 1 ½ cup of white or apple or balsamic or any vinegar of choice—blend and strain –again add to glass container —good fro digestion—regulating HCL production
Anti cancer remedy-anti fungal-anti parasitical-anti viral-anti bacterial
Recipe for Honey and Garlic—Take a whole garlic peeled place in blender—take 3-4 oz of honey—add 2 oz of aloe vera to this—blend til completely fused—then pour everything into a jar and utilize 1 tablespoon increments as needed—potent digestive and intestinal healant—nutritive—strengthening the lower organs and the organs for filtering and lymph system
Garlic Fermented Recipe- Take garlic and place in Jar of Vinegar and date this—shake occasionally—in 6-8 months blend and strain—you have fermented garlic—this will increase the Cysteine Levels and will have a more potent enzyme and Sulfur effect for fighting pathogens and fungi-bacteria or viral and microbial infections
Garlic Oil Recipe— Take a whole bulb of Garlic-Peeled and placed in blender or Manual Extractor ( wheat grass extractor) And add a 1 ¼- oil—use any oil of choice—olive—sunflower—coconut etc and add alcohol ( vodla- gin- white wine 2-3 oz) and then blend this at high speed for 10 minute total—this will heat the oil so be aware you may have to shut down the blender every 3-5 minutes—gauge by touchig the outer blender—if hot then stop blender-allow for cooling or stop process and pour into glass container—ORRR you can take the Garlic extract you made with the alcohol 1-2 oz and add to 3-4 oz of oil and blend for 5 minutes high speed—what you have is a fat regulating antibacterial-anti cancer-antifungal-anti viral anti parasitical regimen—you can as well use this for ear infections by swabbing the ear with this oil mix and then apply a cotton swab
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Show of the Week August 5 2011
BURNS-Solution– Recipe for burns
Apple Cider Vinegar—Remedy and Making
Norway conquers infections by cutting use of antibiotics
Millions were in germ war tests
Green tea extract selectively targets nanomechanics of live metastatic cancer cells— Recipe For making a Green Tea Extract
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BURNS-Solution
A young man sprinkling his lawn and bushes with pesticides wanted to check the contents of the barrel to see how much pesticide remained in it. He raised the cover and lit his lighter; the vapors inflamed and engulfed him. He jumped from his truck, screaming. His neighbor came out of her house with a dozen eggs, yelling: “bring me some eggs!” She broke them, separating the whites from the yolks. The neighbor woman helped her to apply the whites on the young man’s face. When the ambulance arrived and when the EMTs saw the young man, they asked who had done this. Everyone pointed to the lady in charge. They congratulated her and said: “You have saved his face.” By the end of the summer, the young man brought the lady a bouquet of roses to thank her. His face was like a baby’s skin.
Healing Miracle for burns:
Keep in mind this treatment of burns which is included in teaching beginner fireman this method. First aid consists to spraying cold water on the affected area until the heat is reduced and stops burning the layers of skin. Then, spread egg whites on the affected are. One woman burned a large part of her hand with boiling water. In spite of the pain, she ran cold faucet water on her hand, separated 2 egg white from the yolks, beat them slightly and dipped her hand in the solution. The whites then dried and formed a protective layer.–She later learned that the egg white is a natural collagen and continued during at least one hour to apply layer upon layer of beaten egg white. By afternoon she no longer felt any pain and the next day there was hardly a trace of the burn. 10 days later, no trace was left at all and her skin had regained its normal color. The burned area was totally regenerated thanks to the collagen in the egg whites, a placenta full of vitamins.
Recipe for burns—take lavender essential oil and mix in lard—if there is a serious accident then you can swab this on an area to cool of the fire and heal the burn—utilize 1 oz per 1lb of lard and mix it in well—you can melt it down in a container and allow to sit iin hot water til it softens then either with a wisk or a mixer mix the lard and lavender together
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Apple Cider Vinegar—Remedy and Making
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Norway conquers infections by cutting use of antibiotics
2010-01-11, Miami Herald/Associated Press
http://www.miamiherald.com/2010/01/11/1420165/norway-conquers-infections-by.html
At a microscopic level [Aker University Hospital] is pristine. There is no sign of a dangerous and contagious staph infection that killed tens of thousands of patients in the most sophisticated hospitals of Europe, North America and Asia last year, soaring virtually unchecked. The reason: Norwegians stopped taking so many drugs. Twenty-five years ago, Norwegians were also losing their lives to this bacteria. But Norway’s public health system fought back with an aggressive program that made it the most infection-free country in the world. A key part of that program was cutting back severely on the use of antibiotics. Now a spate of new studies from around the world prove that Norway’s model can be replicated with extraordinary success, and public health experts are saying these deaths — 19,000 in the U.S. each year alone, more than from AIDS — are unnecessary. The World Health Organization says antibiotic resistance is one of the leading public health threats on the planet. A six-month investigation by The Associated Press found overuse and misuse of medicines has led to mutations in once curable diseases like tuberculosis and malaria, making them harder and in some cases impossible to treat. Now, in Norway’s simple solution, there’s a glimmer of hope.’
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Millions were in germ war tests
2002-04-21, The Guardian (One of the UK’s leading newspapers)
http://www.guardian.co.uk/politics/2002/apr/21/uk.medicalscience
The Ministry of Defence turned large parts of the country into a giant laboratory to conduct a series of secret germ warfare tests on the public. A government report just released provides for the first time a comprehensive official history of Britain’s biological weapons trials between 1940 and 1979. Many of these tests involved releasing potentially dangerous chemicals and micro-organisms over vast swaths of the population without the public being told. While details of some secret trials have emerged in recent years, the 60-page report reveals new information about more than 100 covert experiments. The report reveals that military personnel were briefed to tell any ‘inquisitive inquirer’ the trials were part of research projects into weather and air pollution. The tests [were] carried out by government scientists at Porton Down. In most cases, the trials did not use biological weapons but alternatives which scientists believed would mimic germ warfare and which the MoD claimed were harmless. But families in certain areas of the country who have children with birth defects are demanding a public inquiry.–
Note: Military personnel were ordered to lie to cover-up potentially dangerous experiments on the public. So how can we trust that these people have the public interest as a priority?
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Green tea extract selectively targets nanomechanics of live metastatic cancer cells.
Nanotechnology. 2011 May 27;22(21):215101-Authors: Cross SE, Jin YS, Lu QY, Rao J, Gimzewski JK
Green tea extract (GTE) is known to be a potential anticancer agent (Yang et al 2009 Nat. Rev. Cancer 9 429-39) with various biological activities (Lu et al 2005 Clin. Cancer Res. 11 1675-83; Yang et al 1998 Carcinogenesis 19 611-6) yet the precise mechanism of action is still unclear. The biomechanical response of GTE treated cells taken directly from patient’s body samples was measured using atomic force microscopy (AFM) (Binnig et al 1986 Phys. Rev. Lett. 56 930). We found significant increase in stiffness of GTE treated metastatic tumor cells, with a resulting value similar to untreated normal mesothelial cells, whereas mesothelial cell stiffness after GTE treatment is unchanged. Immunofluorescence analysis showed an increase in cytoskeletal-F-actin in GTE treated tumor cells, suggesting GTE treated tumor cells display mechanical, structural and morphological features similar to normal cells, which appears to be mediated by annexin-I expression, as determined by siRNA analysis of an in vitro cell line model. Our data indicates that GTE selectively targets human metastatic cancer cells but not normal mesothelial cells, a finding that is significantly advantageous compared to conventional chemotherapy agents.–PMID: 21451222 [PubMed – indexed for MEDLINE]
Recipe For making a Green Tea Extract—take green tea leaves ( get the gunpowder if you can from china it is rolled up during harvest making it ka more potent green tea as well ) take3-4 tablespoons of the leaves and add to a blender then add 1 -1/2 cup of alcohol clear or brandy or wine—then put lid on and blend for 10 minutes and stop blender and strain through a handkerchief –this is one method—be aware that the solution maybe hot so even if you wait til it is cool or til you can handle –safely strain out the green tea through the handkerchief—this is an extract—to make it more potent take the extract and pour a portion into a pot and simmer it down to about half to ¼-1/2 of where you started–Then allow to cool and the bottle—this solution should be good at 3-6 drops 2 times a day—now this is an ultra potent extract
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Show of the Week August 8 2011
‘It has to go away’: Facebook director calls for an end to internet anonymity
EU Regulators and Monsanto Exposed for Hiding Glyphosate Toxicity
How Memory Is Lost– Loss of Memory Due to Aging May Be Reversible
Nootropic Recipe— Nootropic Comboing
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‘It has to go away’: Facebook director calls for an end to internet anonymity
Randi Zuckerberg, marketing director of Facebook has spoken out against internet anonymity in a bid to end cyber bullying Mrs Zuckerberg argued the end of on-line anonymity could help curb the trend of trolling and harassment on the web.–Speaking at a Marie Claire panel discussion on social media, she said: ‘ I think anonymity on the Internet has to go away.[U1]–‘People behave a lot better when they have their real names down. … I think people hide behind anonymity and they feel like they can say whatever they want behind closed doors.'[U2] The comments echo those of former Google CEO Eric Schmidt who has previously labelled internet anonymity a ‘dangerous’ precedent, before predicting government intervention will one day lead to its demise. Controversial: Mark Zuckerberg has recently hit the headlines for proposing to allow under 13s on Facebook –Concerned: Former Google CEO Eric Schmidt has also said previously internet anonymity would possibly come to an end Privacy advocates have however condemned previous attempts to dismantle on-line anonymity. –attacked: Erin Andrews was also present at the meeting to speak about her traumatic experience of cyber bullying—[U3]Critics complain that the forced introduction of some kind of ‘on-line passport’ would damage the freedom of speech and blunt the internet as a tool for dissidents to speak up against oppressive governments.–The panel also pressed Mrs Zuckerberg to list what forthcoming safeguards the site has to protect security, she declined.–She added simply: ‘There’s so much more we can do.—‘We’re actively tying to work with partners like Common Sense Media and our safety advisory committee.’–
The panel were joined by Erin Andrews, an ESPN anchor who had a naked video of her posted on-line by a stalker[U4].–At times becoming emotional, Mrs Andrews asked Mr Schmidt why searches for her name still brought up images and videos of the offending tape, despite her repeated attempts to have them removed.
Adding that just because she was a woman in her 30s She said: ‘It’s still cyber bullying.–‘Somebody needs to step in. As a family we’re always asking, what is it going to take.’–Facebook has previously come under fire after founder Mark Zuckerberg said he would ‘fight’ to allow under-13s to use the social networking website – despite warnings it would put the most vulnerable children at risk.–
In America the age limit, also of 13, is dictated by laws designed to protect young children, but Facebook’s 27-year-old billionaire creator believes the educational benefits of using the site mean the restrictions should be lifted.[U5]
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EU Regulators and Monsanto Exposed for Hiding Glyphosate Toxicity
The European Commission approved glyphosate knowing, as Monsanto did, that it causes birth defects, while the public were kept in the dark, the herbicide –must now be banned. Dr Eva Sirinathsinghji and Dr. Mae-Wan Ho
Please forward widely to your political representatives and demand a worldwide ban on glyphosate herbicides
A damning report co-authored by an international group of scientists and
researchers for non-government organisation Open Earth Source (OES) reveals that studies from industry including those from Monsanto since the 1990s showed glyphosate caused birth defects and the European Commission approved the herbicide in full knowledge of those finding [1]. —Glyphosate is the active ingredient in Monsanto’s Roundup herbicide and over a hundred other commercial formulations. It is the cause of great concern as evidence of its harmful effects keep piling up from independent scientific studies in recent years, including endocrine disruption, DNA damage, reproductive and developmental toxicities, neurotoxicity, cancer, and birth defects (see [2] Glyphosate Toxic and Roundup Worse, SiS 26; [3] Death by Multiple Poisoning, Glyphosate and Roundup, SiS 42; [4] Ban Glyphosate Herbicide Now. SiS 43; [5] Lab Study Establishes Glyphosate Link to Birth Defects, SiS 48).———–
Today, almost 90 percent of the world’s soy production takes place in the US, Brazil and Argentina, and in 2009, RR soybean accounted for 91 percent, 99 percent and 71 percent respectively of total soybean acreage in those countries. ———Since 1997, RR soy production has increased from 5 to 30 million hectares of land in the US alone [1]. Soybeans have been found to contain glyphosate residues up to 10 times as high as the doses that caused foetal malformations in chick and frog embryos.——-With such widespread use of the herbicide, and the EU considering approval of GM crops tolerant to glyphosate for cultivation in Europe, there is an urgent need for a proper review of the herbicide, which is in line with the more stringent new EU pesticide regulation that came into force in June 2011. Indeed, just such a review was due to take place in 2012. But shortly after the EC was notified of the latest research on glyphosate causing birth defects (which the EC dismissed), it delayed the review on glyphosate and 38 other dangerous pesticides to 2015 [U6][1]. Furthermore, the 2010 review will be under the old, less stringent regulations. The official reason for the delay is that they have ‘too much workload’. This means that the safety of glyphosate may not be reviewed under the new regulations until 2030. —The review delay is being challenged in a lawsuit brought against the EC by Pesticides Action Network Europe and Greenpeace. The co-authors of the OES report are also calling on the EC to conduct a prompt review without delay, and to withdraw glyphosate and Roundup from the market.
Evidence of birth defects from industry and independent studies The OES report
reveals that studies carried out by industry in the 1990s showed embryonic lethality and birth defects in laboratory animals, including dilation of the heart in rabbits at low doses of glyphosate. Higher doses were shown to cause defects in independent studies as far back as 1980. —Monsanto has responded by denying its own findings [6]: “Regulatory authorities and independent experts around the world agree that glyphosate does not cause adverse reproductive effects in adult animals or birth defects in offspring of these adults exposed to glyphosate, even at doses far higher than relevant environmental or occupational exposures.”[U7]However, the ‘independent experts’ cited by Monsanto were mired in conflicts of interests, both financial and professional, and rely almost entirely on studies carried out by industry [1]. —Independent studies have revealed links to cancer, genetic damage and endocrine disruption, as well as developmental defects, for example, craniofacial and vertebrae abnormalities in rats [7] as well as craniofacial and mouth deformities, eye abnormalities and bent, curved tails in frog tadpoles [8]. The most recent study by Carrasco and colleagues found a mechanistic link between glyphosate and abnormal retinoic acid signalling in embryonic development [5, 9] ——-Astonishingly, these and numerous other studies cited by the OES report were dismissed by the European Commission (EC) and the German Federal Office for Consumer Protection and Food Safety (BVL), which is responsible for liaising between industry and the EC. BVL’s conclusion, communicated to the EC via Germany’s 1998 ‘draft assessment report’ (DAR), was ‘‘no evidence of teratogenicity” for glyphosate.
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How Memory Is Lost– Loss of Memory Due to Aging May Be Reversible–
The neural networks in the brains of the middle-aged and elderly have weaker connections and fire less robustly than in youthful ones–ScienceDaily (July 28, 2011) — Yale University researchers can’t tell you where you left your car keys — but they can tell you why you can’t find them.—A new study published July 27 in the journal Nature shows the neural networks in the brains of the middle-aged and elderly have weaker connections and fire less robustly than in youthful ones. Intriguingly, the research suggests that this condition is reversible.—“Age-related cognitive deficits can have a serious impact on our lives in the Information Age as people often need higher cognitive functions to meet even basic needs, such as paying bills or accessing medical care,” said Amy Arnsten, Professor of Neurobiology and Psychology and a member of the Kavli Institute for Neuroscience. “These abilities are critical for maintaining demanding careers and being able to live independently as we grow older.”—As people age, they tend to forget things more often, are more easily distracted and disrupted by interference, and have greater difficulty with executive functions. While these age-related deficits have been known for many years, the cellular basis for these common cognitive difficulties has not been understood. The new study examined for the first time age-related changes in the activity of neurons in the prefrontal cortex (PFC), the area of the brain that is responsible for higher cognitive and executive functions.—Networks of neurons in the prefrontal cortex generate persistent firing to keep information “in mind” even in the absence of cues from the environment. This process is called “working memory,” and it allows us to recall information, such as where the car keys were left, even when that information must be constantly updated. This ability is the basis for abstract thought and reasoning, and is often called the “Mental Sketch Pad.” It is also essential for executive functions, such as multi-tasking, organizing, and inhibiting inappropriate thoughts and actions. Arnsten and her team studied the firing of prefrontal cortical neurons in young, middle-aged and aged animals as they performed a working memory task. Neurons in the prefrontal cortex of the young animals were able to maintain firing at a high rate during working memory, while neurons in older animals showed slower firing rates. However, when the researchers adjusted the neurochemical environment around the neurons to be more similar to that of a younger subject, the neuronal firing rates were restored to more youthful levels.—-Arnsten said that the aging prefrontal cortex appears to accumulate excessive levels of a signaling molecule called cAMP, which can open ion channels and weaken prefrontal neuronal firing. Agents that either inhibited cAMP or blocked cAMP-sensitive ion channels were able to restore more youthful firing patterns in the aged neurons. One of the compounds that enhanced neuronal firing was guanfacine, a medication that is already approved for treating hypertension in adults, and prefrontal deficits in children, suggesting that it may be helpful in the elderly as well.—Arnsten’s finding is already moving to the clinical setting. Yale is enrolling subjects in a clinical trial testing guanfacine’s ability to improve working memory and executive functions in elderly subjects who do not have Alzheimer’s Disease or other dementias.-Story Source-The above story is reprinted (with editorial adaptations by ScienceDaily staff) from materials provided by Yale University.–Journal Reference-Min Wang, Nao J. Gamo, Yang Yang, Lu E. Jin, Xiao-Jing Wang, Mark Laubach, James A. Mazer, Daeyeol Lee, Amy F. T. Arnsten. Neuronal basis of age-related working memory decline. Nature, 2011; DOI: 10.1038/nature10243
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Nootropic Recipe
—Nootropics are substances that enhance the efficiency of brain activity from memory –analytical thinking-creative thinking—communication between brain cells—neurol networking throughout the body-Brain Health and Support—what we are going to do is to take Rosemary and Sage in equal weight and put into a blender we are going to add Coffee Bean as well 1-2 tablespoon –and we are going to initially grind these together in a powder and then when powdered down will add blue berries and walnuts ¼ cup of each and again blend til smooth and saturated—you can add more walnuts or pecans to this till you get it to a thickened level desired—when done add to glass jar and consume –straight up in the morning with an egg breakfast with potato ( remember eggs are brain foods)—will see the brain receptors ( over time) improve in memory—dreaming—and coordination—level of alertness will improve as well—as a option you can as well add the essential oil of rosemary and the essential oil of sage and bay leaf to this at about 3 drops —even thyme ( which increases DHA production) blend til the Essential oils are saturated into the mix –do this at the beginning of the stage
Nootropic Comboing—here are some things to try—
Piracetam 300-500mgs + Choline 250-500mgs+ DMAE 250-500mgs—
Another combo would be to take Sulbatiamine 200 mgs+ Piracetam 500 mgs + Centrophoxine 250—this will cause increase brain energy and alertness and preserve the Acetylcholine as well
B12 2000-5000mcgs + Coffee ( 1 cup or 1 tsp of the solution you just made ) + peppermint essential oil 1 drop in the coffee—extreme alertness and clarity for the brain
Pyritrinol 200 mgs + Sulbatiamine 200 mgs + Piracetam 500mgs —this increase the antioxidant levels in the brain a well as the bette utilization of glucose for brain energy
Egg Yolk or Sunflower Lecithin 1-2 caps 2 times a day+ Wheat Germ Oil 1 tsp 2 + CQ10 or Idebenone 100mgs 2 times a day regeneration the Myelin sheath around the brain and other cells—increased oxygen and acetylcholine as well antioxidant support for the fats being used
Teas with Rosemary + Sage + Thyme + Bay Leaf—in equal weight in 2 pints ( litres) of distilled or reverse osmosis water will as well preserve the brain cells and as well increase the antioxidant elements throughout the body
Other herbs that are a good choice would be Rhodiola 500mgs ( with the right ratio od saldrosoides and rosavins ) + rosemary 500mgs + b12
Another thing to consider as well is Iodine ( lugols or Iodoral 12.5 mgs) + tyrosine 500mgs + selenium may have an anti depressing element as well
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[U1]This Person Needs To Go AWAY BROKE –BUSTED—STALKED –SPY’d On—AND Denied total ACCESS to PERSONAL PRIVACY—bet she will Kiss someones Arse for her autonomy then!!!
[U2]People Should be able to say what they want to—in any format—that is what freedom of speech dictates—some things maybe hurtful and vindictive—but that’s as well part of it—the moment there is sensorship—there will be an outbreak—In Canada they call it hate speech because we had some feminized politicians that were spoken hard to and as a result they passed these so called Hate Speech laws —people for the most part still speak there mind and in DEFIANCE to bad laws like this —whne the gov’t pass laws like this and no one responds then they have a good gauge on how domesticated people have become and how much more easily they can abuse there citizenry!!!
[U3]OHH possibly she needs a sooter now—the poor suck!!!
[U4]HOWWW does some one get a video of you being Naked!!!??? Unless you made yourself available for this—-this is what amazes me you can display yourself in some format and allow people to see you in a compromised way and then you allow yourself photo’d and when someone puts this out there you feel bullied???-Stupidity must be in abundance here and some must really think this is a gift being stupid!!!
[U5]This is such an oxymoron—on one hand you want total full disclosure and on the other you want to allow 13 year olds to get in on being disclosed or totally exposed allowing for pedophile activity—seems to me this 27 year old has some sexual inadequacies and needs to address his manhood and leave soy alone
[U6]Sounds like Democide to me !!!!
[U7]Monsanto with it’s “Science” I bet they have Genetically modified the Moon to grow Canadian Cheese there to and we fly it direct to the stores from the moon!!! See how scientific this sounds—Production of Cheese on the Moon with Monsanto GMO CHEESE !!!
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Show of the Week August 12 2011
Lyme Disease Tick Adapts to Life On the (Fragmented) Prairie
Dead Cats And Dogs Used To Make Pet Food
Injected Cells Cure Tumors in Mice
Building Muscle Can Lower Person’s Risk of Insulin Resistance
New Target Found for Nitric Oxide’s Attack On Salmonella Bacteria
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Lyme Disease Tick Adapts to Life On the (Fragmented) Prairie
ScienceDaily (June 22, 2011) — A new study offers a detailed look at the status of Lyme disease in Central Illinois and suggests that deer ticks and the Lyme disease bacteria they host are more adaptable to new habitats than previously appreciated.–Led by researchers at the University of Illinois, the study gives an up-close view of one region affected by the steady march of deer ticks across the upper Midwest. Their advance began in Wisconsin and Minnesota and is moving at a pace of up to two counties a year in Illinois and Indiana.—Today the deer tick is established in 26 Illinois counties, up from just eight in 1998, said Illinois Department of Public Health entomologist Linn Haramis. Reports of human Lyme disease cases in the state have more than tripled in the same period[U1], he said.–“We’ve had several years in a row where we’ve had over 100 cases, up from about 30 per year more than 10 years ago,” Haramis said. “It’s not a huge increase, but it’s been steady and there’s an upward trend.”—Deer ticks are known to do best in forested areas, where they can readily move from small mammals (which provide their first meal) to moist leaf litter on the forest floor, and then to deer, on which they mate. Deer ticks do not pick up the Lyme infection from deer, said Jennifer Rydzewski, who completed her master’s degree with the study in the department of natural resources and environmental sciences at the University of Illinois.–“The deer tick will feed on a variety of mammals, birds and even reptiles,” she said. “But Borrelia burgdorferi, the bacterium that causes Lyme disease, replicates really well within white-footed mice, so white-footed mice are the main reservoir that passes that bacterium on to the immature ticks that are feeding on it.”–White-footed mice also are forest dwellers. Prior to the new study, little was known about whether, or how, Lyme disease persists in other habitat types.—To determine if Lyme disease had gained a foothold in the patchwork of forests, farms and prairies of Central Illinois, researchers trapped small mammals in Allerton Park, a 1,500-acre (600-hectare) natural area in Piatt County. They focused on four habitat types: young forest, mature forest, a flood plain and a 30-acre (12-hectare) patch of prairie surrounded by woods and agricultural fields.—The researchers removed deer ticks from the mammals they trapped and tested the ticks for Lyme disease. They found that the immature forest and the prairie hosted the highest percentage of deer-tick-infested mammals, the highest number of ticks per mammal trapped and the highest rates of ticks infected with Lyme disease of the four habitat types evaluated.—“The highest prevalence of B. burgdorferi infection was found (in deer tick larvae) from the prairie (27 percent) followed by the young forest (15 percent), the mature forest (6 percent) and the flood plain (6 percent),” the researchers wrote.–[U2]”Interestingly, all of the positive ticks from the prairie were from prairie voles, not the typical white-footed mouse,” Rydzewski said. There also were many more ticks per animal on the prairie voles than on the white-footed mice of the forest, she said.
This is the first study to report evidence that the prairie vole may potentially serve as a competent reservoir host for the Lyme disease bacterium, B. burgdorferi, said Nohra Mateus-Pinilla, a wildlife veterinary epidemiologist at the Illinois Natural History Survey who led the study with Rydzewski and natural resources and environmental sciences emeritus professor Richard Warner. (The Survey is a unit of the Prairie Research Institute at Illinois.)–“The fact that we found tick larvae feeding so prominently on prairie voles and those ticks were infected and hadn’t had a chance to feed on anything else is a very strong indicator that we are dealing with a different reservoir of Lyme disease that deserves more attention,”[U3] Mateus-Pinilla said.—The researchers hypothesize that when newly hatched ticks find themselves on the prairie, they latch on to the first small mammal that comes along, which in most cases is a prairie vole (white-footed mice prefer the forest). The abundance of prairie voles in the prairie is much lower than that of the white-footed mice in the forest, so more tick larvae and nymphs end up on the same few prairie voles. Since the number of ticks per animal is higher on the prairie, the likelihood of infection is higher there as well.—“The landscape of Illinois, especially the northern and central area, is very fragmented with agricultural and other development, so there aren’t really big continuous areas that are forested,” Rydzewski said. “And so maybe these ticks are finding new habitats to establish themselves in because of the lack of previous habitats.””What’s exciting about the new findings is that we are dealing with potentially new mechanisms of disease transmission that we just have not explored and perhaps we do not understand,”[U4] Mateus-Pinilla said. “We need to think outside of what we already know about Lyme disease transmission.”–The new study appears in the journal Vector-Borne and Zoonotic Diseases. Researchers from the U. of I. department of pathobiology and Michigan State University also contributed to this study.Story Source-he above story is reprinted (with editorial adaptations by ScienceDaily staff) from materials provided by University of Illinois at Urbana-Champaign.
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Injected Cells Cure Tumors in Mice
2006-05-09, Los Angeles Times
http://articles.latimes.com/2006/may/09/science/sci-cancer9
White blood cells from mice that are naturally immune to cancer cured tumors in other mice and provided them with lifelong immunity to the disease, researchers reported Monday. The finding indicates the existence of a biological pathway previously unsuspected in any species. A small team of researchers is working to understand the genetic and immunological basis of the surprising phenomenon. Preliminary studies hint at the existence of a similar resistance in humans. Researchers hope that harnessing the biological process could lead to a new approach to treating cancer. But Dr. Zhen Cui of Wake Forest, whose team published the findings in the Proceedings of the National Academy of Science, said he expected rapid replication of the results because the findings were so clear-cut and easily observed. “This is a truly remarkable phenomenon — and it really needs confirmation from other institutions,” he said. The team took white blood cells from the immune mice … and injected them into mice already carrying a variety of tumors, some of which were extremely aggressive. In every case, the cancers were destroyed, even if the cells were injected at a point distant from the tumor. Healthy tissues were not affected. The mice that received the cells, furthermore, were protected from new tumors for the rest of their lives. The researchers have no idea how the immunity continues.
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Building Muscle Can Lower Person’s Risk of Insulin Resistance Increased Muscle Mass May Lower Risk of Pre-Diabetes
ScienceDaily (July 28, 2011) — A recent study accepted for publication in The Endocrine Society’s Journal of Clinical Endocrinology & Metabolism(JCEM) found that the greater an individual’s total muscle mass, the lower the person’s risk of having insulin resistance, the major precursor of type 2 diabetes.—-With recent dramatic increases in obesity worldwide, the prevalence of diabetes, a major source of cardiovascular morbidity, is expected to accelerate. Insulin resistance, which can raise blood glucose levels above the normal range, is a major factor that contributes to the development of diabetes. Previous studies have shown that very low muscle mass is a risk factor for insulin resistance, but until now, no study has examined whether increasing muscle mass to average and above average levels, independent of obesity levels, would lead to improved blood glucose regulation.—“Our findings represent a departure from the usual focus of clinicians, and their patients, on just losing weight to improve metabolic health,” said the study’s senior author, Preethi Srikanthan, MD, of the University of California, Los Angeles (UCLA). “Instead, this research suggests a role for maintaining fitness and building muscle. This is a welcome message for many overweight patients who experience difficulty in achieving weight loss, as any effort to get moving and keep fit should be seen as laudable and contributing to metabolic change.”—-In this study, researchers examined the association of skeletal muscle mass with insulin resistance and blood glucose metabolism disorders in a nationally representative sample of 13,644 individuals. Participants were older than 20 years, non-pregnant and weighed more than 35 kg. The study demonstrated that higher muscle mass (relative to body size) is associated with better insulin sensitivity and lower risk of pre- or overt diabetes.—-“Our research shows that beyond monitoring changes in waist circumference or BMI, we should also be monitoring muscle mass,” Srikanthan concluded. “Further research is needed to determine the nature and duration of exercise interventions required to improve insulin sensitivity and glucose metabolism in at-risk individuals.”—Also working on the study was Arun Karlamangla, PhD, MD, of the David Geffen School of Medicine at UCLA.–Story Source-The above story is reprinted (with editorial adaptations by ScienceDaily staff) from materials provided by The Endocrine Society, viaEurekAlert!, a service of AAAS.–Journal Reference-P. Srikanthan, A. S. Karlamangla. Relative Muscle Mass Is Inversely Associated with Insulin Resistance and Prediabetes. Findings from The Third National Health and Nutrition Examination Survey. Journal of Clinical Endocrinology & Metabolism, 2011; DOI: 10.1210/jc.2011-0435
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New Target Found for Nitric Oxide’s Attack On Salmonella Bacteria
ScienceDaily (July 23, 2011) — A new target for nitric oxide has been revealed in studies of how it inhibits the growth of Salmonella. This bacterium is a common cause of food-poisoning.—“Nitric oxide is naturally produced in the nose and the gut and other tissues in the body to ward off infection,” explained the senior author of the paper, Dr. Ferric Fang. He is a University of Washington (UW) professor of laboratory medicine, microbiology and medicine.–Nitric oxide — not to be confused with nitrous oxide, the laughing gas in dentists’ offices — is similar to the preservatives in hotdogs, Fang said. Reactive nitrogen species, like nitric oxide, make brown meat an appetizing pink. They also weed out microorganisms that spoil food or cause food poisoning.—Fang’s lab has made several important discoveries on ways mammals exploit the biochemical properties of nitric oxide to defend themselves from germs. Nitric oxide, a key actor in the body’s innate immune defenses, apprehends a rogue’s gallery of disease-causing organisms.
The newest results underscore that nitric oxide’s antimicrobial actions are due to its interference with the metabolism, or energy production, of pathogens.—“Nitric oxide imposes substantial metabolic restrictions on bacteria,” the researchers noted. Fang explained that its reactions with numerous metabolic targets accounts for the broad-spectrum nature of its success. It keeps many types of disease-causing bacteria at bay. It also prevents an overgrowth of the body’s many helpful bacteria.—The latest report on the versatility of nitric oxide in arming hosts against pathogens is published in the July 21 issue of Cell Host & Microbe. Dr. Anthony R. Richardson, who is now at the University of North Carolina at Chapel Hill, led the research while he was a postdoctoral fellow in the Fang lab. –Fang’s team looked at the multi-pronged action of nitric oxide on Salmonella enterica serovar Typhimurium. This type of Salmonella can contaminate food and is similar to the bacteria that cause typhoid fever.–Nitric oxide and related chemicals put Salmonella into a difficult situation called nitrosative stress. When exposed to nitric oxide, Salmonella is unable to make two essential amino acids, methionine and lysine.—-Without these, Salmonella cannot grow.—“This is bad news for the bacteria, but not for the host,” Fang said. “Nitric oxide doesn’t damage the host that produces it.”–
The ability to withstand nitrosative stress makes some forms of bacteria more virulent than milder types that can’t handle it.—Richardson and his colleagues found that nitric oxide and its cousins throw a monkey wrench into several points in the Krebs cycle, also known as the tricarboxylic acid cycle. This cycle is the second stage in cellular respiration, when fuel is broken down to release energy for cell growth and division.—The researchers outlined how multiple interruptions in this cycle create a series of biochemical consequences that starve Salmonella of methionine and lysine. Nitric oxide also blocks certain regulatory genes that otherwise would give Salmonella an alternate chemical route out of its distress.–“Collectively, this work demonstrates that nitric oxide imposes substantial metabolic restrictions on bacteria,” the authors concluded.—In a commentary on these findings, Dr. Stephen Spiro of the Department of Molecular and Cell Biology at the University of Texas at Dallas wrote that the work “focuses renewed interest in central metabolic pathways as nitric oxide targets.”-“More generally,” he noted, “this study provides an excellent illustration that a proper understanding of host-pathogen interactions and the development of therapeutic interventions require a detailed knowledge of pathogen metabolism.”—Nitric oxide’s targeting of the Krebs cycle is not unique to Salmonella. In learning how the body naturally controls the energy supplies and growth of varied disease-causing organisms, Fang said, scientists may be able to develop new broad-spectrum antimicrobials that mimic these effects[U5], drugs that promote the body’s own natural defenses against infection, or agents that overcome the ways virulent bacteria compensate when being starved of certain nutrients.—The research was supported by grants from the National Institutes of Health.–Story Source:–The above story is reprinted (with editorial adaptations by ScienceDaily staff) from materials provided by University of Washington. The original article was written by Leila Gray.—Journal Reference-Anthony R. Richardson, Elizabeth C. Payne, Noah Younger, Joyce E. Karlinsey, Vinai C. Thomas, Lynne A. Becker, William W. Navarre, Margaret E. Castor, Stephen J. Libby, Ferric C. Fang. Multiple Targets of Nitric Oxide in the Tricarboxylic Acid Cycle of Salmonella enterica Serovar Typhimurium. Cell Host & Microbe, 21 July 2011; 10(1) pp. 33 – 43 DOI: 10.1016/j.chom.2011.06.004
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[U1]GEO Manipulation of DNA and Genetics causing the impbalance
[U2]It appears they do not like water and a mature forest which would hold water and other anti bacterial elements that a forest fully matured would have developed
[U3]Another rogue Military experiment Perhaps—to release pathogens and infections- Bio genetics ?
[U4]Again Military Experimentation???
[U5]In other words Natural methods are effective and the Drug industry has not yet understood the means of creating or mimicking there efficiency or effectiveness
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Show of the Week August 15 2011
Sodium
List of High-Protein Foods and Amount of Protein in Each
Foods High in Protein–Dry Measure Equivalents
Wafting poison makes fertile ground for suit in Stearns County
Peanuts—Black Seed- Nobileton-Rosemary-
Recipe for a Peanut Butter Delight
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Sodium
People who crave Sodium (Salt) are often found to be suffering from Adrenal Insufficiency.
Cardiovascular System
Sodium increases the viscosity (thickness) of Blood.
Sodium may help to regulate osmotic Blood Pressure:
Caution: excess Sodium may increase Blood Pressure.
Sodium may alleviate Hypotension
Cells
60% of the body’s stored Sodium is in the fluids surrounding the Cells (extracellular) and 10% concentrates inside the body’s Cells (in the Intracellular Fluid):
-Sodium is the principal anion (negatively-charged Ion) in the Intracellular Fluid.
Sodium may reverse Acidosis.
Sodium is one of the body’s primary Electrolytes.
Digestive System
Sodium may alleviate Constipation.
Sodium Sulfate may alleviate Diarrhea.
Flatulence may occur as a result of Sodium deficiency.
Nausea may occur as a result of Sodium deficiency
Vomiting may occur as a result of Sodium deficiency.
Excretory System
Optimal (but not excessive) Sodium levels are required for the correct function of the Kidneys.
Eyes/Vision
Sodium deficiency may cause Blurred Vision.
Immune System
Sodium may help to reduce Fevers.
Optimal Sodium levels are required for the correct function of the Lymphatic System (Sodium is a component of Lymph). [more info]
Musculoskeletal System
30% of the body’s Sodium concentrates in the Bones.
Correct Potassium:Sodium balance is essential for the correct function of the
Muscles—-Shrinkage of the Muscles can occur as a result of Sodium deficiency.
Sodium may facilitate proper Muscle contraction. [more info]
Muscle Cramps may occur as a result of Sodium deficiency.
Nervous System
Apathy may occur as a result of Sodium deficiency.
Impaired Concentration ability may occur as a result of Sodium deficiency.
Confusion may occur as a result of Sodium deficiency
Severe Sodium deficiency may cause Hallucinations.
Memory impairment may occur as a result of Sodium deficiency.
Sodium may facilitate the conduction of Nerve Impulses in the Cell Membranes of the Nervous System
Sodium may alleviate Heat Stroke.
Water & Water Balance
Sodium may alleviate Dehydration (by facilitating the retention of Water). Sodium regulates the body’s Water Balance (by causing the retention of Water) – Sodium helps to maintain a normal balance of Water between the body’s Cells and surrounding fluids:
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List of High-Protein Foods and Amount of Protein in Each
Foods High in Protein
High-Protein Foods
Shortcut: An ounce of meat or fish has approximately 7 grams of protein.
Beef
Hamburger patty, 3 oz – 28 grams protein
Steak, 4 oz – 42 grams
Most cuts of beef – 9 grams of protein per ounce
Chicken
Chicken breast, 3.5 oz – 30 grams protein
Chicken thigh – 10 grams (for average size)
Drumstick – 11 grams
Wing – 6 grams
Chicken meat, cooked, 3 oz – 35 grams
Fish
Most fish fillets or steaks are about 22 grams of protein for 3 ½ oz (100 grams) of cooked fish, or 6 grams per ounce About 20 grams per 3 oz
Tuna, 6 oz can – 40 grams of protein
Pork
Pork chop, average – 22 grams protein
Pork loin or tenderloin, 4 oz – 29 grams
Ham, 3 oz serving – 19 grams
Ground pork, 1 oz raw – 5 grams; 3 oz cooked – 22 grams
Bacon, 1 slice – 3 grams
Canadian-style bacon (back bacon), slice – 5 – 6 grams
[U1]
Eggs and Dairy
Egg, large – 6 grams protein
Milk, 1 cup – 8 grams
Cottage cheese, ½ cup – 15 grams
Yogurt, 1 cup – usually 8-12 grams, check label
Soft cheeses (Mozzarella, Brie, Camembert) – 6 grams per oz
Medium cheeses (Cheddar, Swiss) – 7 or 8 grams per oz
Hard cheeses (Parmesan) – 10 grams per oz
Nuts and Seeds
Peanut butter, 2 Tablespoons – 8 grams protein
Almonds, ¼ cup – 8 grams
Peanuts, ¼ cup – 9 grams
Cashews, ¼ cup – 5 grams
Pecans, ¼ cup – 2.5 grams
Sunflower seeds, ¼ cup – 6 grams
Pumpkin seeds, ¼ cup – 8 grams
Flax seeds – ¼ cup – 8 grams
Dry Measure Equivalents
3 teaspoons 1 tablespoon 1/2 ounce 14.3 grams
2 tablespoons 1/8 cup 1 ounce 28.3 grams
4 tablespoons 1/4 cup 2 ounces 56.7 grams
5 1/3 tablespoons 1/3 cup 2.6 ounces 75.6 grams
8 tablespoons 1/2 cup 4 ounces 113.4 grams
12 tablespoons 3/4 cup 6 ounces .375 pound
32 tablespoons 2 cups 16 ounces 1 pound
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Wafting poison makes fertile ground for suit in Stearns County
Oluf Johnson’s 1,500-acre farm in Stearns County is an organic island in a sea of chemically treated corn and soybeans.—Improperly applied pesticides repeatedly drift over from neighboring farms, often with dire consequences for Johnson. But now, thanks to a new court ruling, he and other farmers can sue to recover their losses.—Letting damaging chemicals cross property lines is trespassing, the Minnesota Court of Appeals ruled on Monday. Moreover, since those pesticides made his crop unsalable in the organic market, Johnson is entitled to damages from the company that applied it, the Paynesville Farmers Union Cooperative Oil Co., the court said.—“Whenever this happens it will give people with overspray a legal avenue to pursue,” said Doug Spanier, an attorney with the Minnesota Department of Agriculture, which administers pesticide enforcement regulations in the state. And that could go for any farmer whose crop is made inedible by someone else’s chemical spray and even homeowners whose property has been damaged by a neighbor’s overuse of RoundUp, legal experts said.–
It’s one case among many across the country that illustrate how the fight over pesticide use is becoming increasingly contentious. Consumers and health experts are worried about the consequences of pesticides and herbicides in the food chain, and the demand for organically grown food is rising in lockstep.
Courts are responding—Recently, an organic farmer in California won $1 million in damages when pesticides were carried by fog from faraway fields to his own. He had to throw away a season’s worth of herbs destined for organic markets.—The Minnesota court’s decision on Monday “puts it in line with how other jurisdictions have dealt with this,” said Alexandra Klass, a professor of environmental law at the University of Minnesota. “The vast majority of jurisdictions find that pesticide drift is a trespass.”—
The state Agriculture Department said it fields 100 to 150 complaints a year from farmers about overspraying. But only about 35 a year result in some kind of financial penalty, state agriculture officials said.—For Johnson and his wife, Debra, it’s been a long, hard fight. Their attorney, Arlo Vande Vegte of Long Lake, said they would not comment on the decision because talking about it publicly could jeopardize their case. It will get another hearing in Stearns County District Court, where it was originally dismissed, he said.—But their story was detailed by the appeals court.—The Johnsons made the decision to become organic farmers in the 1990s, an arduous process that takes at least three years of careful planning and scrupulous record keeping. They asked the local pesticide cooperative, Paynesville Farmers Union, to take precautions with spraying around the farm.—Nonetheless, the cooperative repeatedly sprayed pesticide and herbicide on neighboring fields in a way that violated Minnesota law, the court said in its decision.—The attorney representing the cooperative did not return phone calls on Monday.
The first time it happened in 1998, the cooperative apologized but refused to pay the Johnsons for the damage caused by the overspraying. When it happened again in 2002, Johnson complained to the Agriculture Department, which determined the chemicals had been sprayed illegally, tainting Johnson’s crop.—He sold it at lower, nonorganic prices, and, following federal rules, removed the contaminated field from production for three years. That time the cooperative settled out of court with the Johnsons.–But it happened again in 2005, 2007 and 2008. In all, the state cited the cooperative four times for violating pesticide laws by applying the chemicals on windy days.—-But the Johnsons also paid a price each time it happened. They had to burn fields and plow under soybeans and take their fields out of production. In 2009 they sued the co-op, charging negligence and trespassing.—-But the district court threw out the suit, saying Minnesota does not recognize trespassing “by particulate matter,” and that the Johnsons could not prove damages. The Appeals Court disagreed. It said that thrown objects and even bullets constitute trespass, and that the state Supreme Court has ruled that beekeepers can collect damages for pesticide-contaminated bees that destroyed their hives.—Perhaps even more significant for other organic farmers, the Johnsons’ attorney said, they are entitled to damages because they couldn’t sell their tainted crops in the organic market.
Recipe For a Peanut Butter Delight—– You will need honey–Nut of Choice–Rosemary extract or dried ( if dried use one tablespoon) –Black seed extract or dried ( if dried use 1 tablespoon) and Tangerine essential oils 20 drops -Creatine 20 grams Cinnamon Powder 1 tablespoon and Cardamon powder 1 tablespoon–take 6 oz of honey and allow to blend for about 5 minutes til almost liquefying oor really soft flowing—then take 20 grams of Creatine—add 1 oz of Black Seed Extract—add ! oz of rosemary extract -Add 20 drops of tangerine essential oils—allow to fuse then add Cinnamon Powder 2 oz and add Cardamon 3 tablespoons and as it is fusing start adding peanuts in small increments you will eventually need a cup ( more or less depending on how thick you like it—allow to blend till everything looks completely fused—then when done pour into a glass container— consume as you like –straight up out of the jar or add to smoothie or a ice cream delight ( non soy and no artificial flavoured or canola—the protein is high and the other nutritional values are as well to protect the system and enhance the strength and endurance and immunitiy
TOP D
[U1]If you have a sugar issue do not use—utilize a better source and there are choices
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Show of the Week August 19 2011
A non-animal sourced, ‘human’ version of the gelling agent gelatine
EMFs exposure, asthma linked in kids
8 Reasons Raw Foodies Are Dangerous Extremists (Satire)
Flea Removal – Flea Extermination with Your Vinegar Home Flea Remedies
Aerosols Affect Climate More Than Satellite Estimates Predict
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Researchers produce alternative to animal-sourced gelatine
By Nathan Gray, 20-Jul-2011
A non-animal sourced, ‘human’ version of the gelling agent gelatine has been produced by researchers in China.
Writing in Journal of Agricultural and Food Chemistry, the researchers based at the Beijing University of Chemical Technology, report a new method for creating large quantities of fermentation-derived gelatine which they say could, in theory, become a substitute for animal-based gelatine currently used in many food products. —–The researchers, led by Jinchun Chen from Beijing University, successfully produced the alternative by genetically engineering yeast cells to produce that same version of the of the gelling agent that humans naturally produce. -Public perception —A report by US-based Global Industry Analysts (GIA) recently highlighted public concerns regarding use of animal-sourced gelatine – and the rise of vegetarian and vegan alternatives – means industry will likely to see a shift away from the use of animal-derived gelatine. —The GIA report noted that the global gelatine market is growing fast, driven by increasing demand for gelatine for food production in developing countries and as a biomaterial in cosmetics.
“Processors are already seeking substitutes for animal-sourced ingredients. While these alternatives meet some gelatine characteristics, none is yet available that matches all the functions such as gelling, binding, thickening, stabilizing, film forming, and aerating properties,” said the GIA. –Practical issues —Gelatine is widely used as a gelling agent in many industries, including pharmaceuticals, cosmetics, and particularly in the food industry, because of its unique properties. —“The current methods of making gelatine involve the extraction of collagen from animal tissue (skin and bone of bovine or porcine) and its conversion to gelatine, which is later isolated by acid, base, or enzymatic extraction methods,” said the researchers.
Chen and his colleagues noted that that from a functional point of view, gelatine produced from animal sources are often mixtures of polypeptides of different sizes and charges – meaning that the products can vary greatly and have severe effects on gel-forming capacity. —In addition, they said that animal-sourced gelatine will always carry a risk of associated infectious diseases, such as bovine spongiform encephalopathy, and can also cause immune hypersensitivity when consumed by humans. –[U1]Useful alternative? —“On the contrary, production of human gelatine[U2] in a microbial expression system may eliminate the aforementioned problems because the size and charge of human gelatine can be easily controlled,” said Chen and his team. [U3]–“Moreover, scaling up production of the desired product by DNA manipulation and bioengineering-related techniques in microbial expression system is feasible … These advantages of recombinant gelatine have attracted increasing interest from research and industrial circles,[U4]” they added. By inserting human gelatine genes into the yeast strain Pichia pastoris, using genetic engineering techniques, the cells are then able to produce the ‘human’ form quickly and efficiently. —Chen and his team also noted that the human-yeast gelatine is more stable than animal-based gelatine, which can have a high variability from batch to batch – meaning the new method may offer greater quality control on the production line. —Source: Journal of Agricultural and Food Chemistry—Volume 59, Issue 13, Pages 7127–7134, doi: 10.1021/jf200778r “New Strategy for Expression of Recombinant Hydroxylated Human-Derived Gelatin in Pichia pastoris KM71” Authors: H. Duan, S. Umar, R. Xiong, J. Chen
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EMFs exposure, asthma linked in kids
Tue Aug 2, 2011 11:42AM GMT
The children of mothers who were highly exposed to electromagnetic fields (EMFs) during pregnancy are more likely to develop asthma, a US study says. –Researchers at the Kaiser Permanente in Oakland, California, gave 801 pregnant women tiny monitors to wear during pregnancy. The monitors recorded the expectant mothers’ exposure to low-frequency magnetic fields emitted from electric and electronic devices such as microwaves, fans, fluorescent light bulbs, vacuum cleaners, coffee grinders and power lines or stations. —However, the monitors didn’t measure the individual’s exposure to higher frequency electromagnetic fields generated by mobile phones and cell-phone towers. —Scientists then followed the mothers until their children turned 13. According to the results, about 21 percent of the kids were diagnosed with asthma, most of them before the age of five. —The risk of developing asthma among children born to mothers with the highest EMFs exposure was 3.5 times higher than their peers born to women with the lowest radiation level, said the report published in the Archives of Pediatrics & Adolescent Medicine. —The results also revealed that the first-born children and those born to mothers with a history of asthma are more vulnerable to developing asthma, wrote Dr. De-Kun Li and his colleagues. –Previous studies found an association between higher exposure to EMFs during pregnancy and increased risk of miscarriage. —According to some animal studies, EMFs can affect the immune system and subsequently increase the risk of developing asthma. —Researchers warned about the great risk of serious public health problems due to the individuals exposed to magnetic fields through everyday life.
Li suggested that pregnant women should lower their daily exposure to known magnetic field sources and keep distance while using electronic and electric devices.