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    Zeaxanthin improves elderly vision
     
    Elderly people have better night vision and are better able to discern fine details, when taking zeaxanthin, a military study has found. The study followed 60 war veterans with early signs of Age-Related Macular Degeneration (AMD) who were given 8mg of zeaxanthin daily. They showed a better ability to drive at night and improved reading of an eye chart between 1.5 and 8.5 lines. Blind spots also improved. — The study followed 60 elderly veterans with early over a 12-month period that consumed 8 mg of dietary Zeaxanthin daily, showed improvement in the ability to drive at night, recognition of fine detail – an average improvement of 1.5 lines or 8.5 letters on an eye chart, and the disappearance of blind spots. — The study was led by Stuart Richer, PhD, OD at the Veterans Administration Hospital in Chicago, and published in the November issue of the Journal of Optometry . AMD is a degenerative retinal disease that causes central vision loss and leaves only peripheral vision, and the leading cause of legal blindness for people over 55 years of age in the Western world, according to AMD Alliance International. Those in the study were given either 8mg of zeaxanthin, 9mg of lutein, or a combination of both daily over a 12-month period. All groups improved in the vision measures tested. —“In older male patients [zeaxanthjin improved] foveal cone-based visual parameters, whereas [lutein] enhanced those parameters associated with gross detailed rod-based vision, with considerable overlap between the 2 carotenoids,” the researchers found. –“The equally dosed (atypical dietary ratio) [zeaxanthin plus lutein] fared worse in terms of raising MPOD [macula pigment optical density], presumably because of duodenal, hepatic-lipoprotein or retinal carotenoid competition. These results make biological sense based on retinal distribution and [zeaxanthin] foveal predominance.” — Source- Journal of the American Optometric Association — November– ‘Randomized, double-blind, placebo-controlled study of zeaxanthin and visual function in patients with atrophic agerelated macular degeneration’ Authors: Richer et al
     
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    Recipe for the Eyes—
    Cheapest form of Zeaxanthin- would be paprika—so if you combine marigold and paprika then you get the benefit of both the lutein and zeaxanthin—easiest way take the marigold put in a blender 1 cup of the flower dry or fresh add ¼ cup of paprika—1 oz of vodka ( 2 if necessary ) add oil of choice—olive-sunflower-almond-coconut—top of the flower or just about ½ inch ( 1 centimeter) above—blend at high speed ( start out at a slow speed and when the blender gets going then rev it up to high ) for about 5-7 minutes—this will create a centrifuge and extract the components into the oil —when done stop the blender and strain through a handkerchief or pillow case or a cloth where you can squeeze out the oil—this will have absorbed the components and you have a remedy—take 1 tsp of this several times a day—if you wish to extend the life of the oil then add 1 drop of the essential oil of rosemary to the bottle and shake well—then utilize
     
    TOP C
     
    [U1]Aspartame increases sugar addiction and is a neurol toxin
    [U2]In other words the high court of the regulators have been paid off
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    HOME
     
    Show of the Week December 12 2011
     
    Professional Dental Cleanings May Reduce Risk of Heart Attack, Stroke
     
    Enzymatic Synthesis of Pyrrolysine, the Mysterious 22nd Amino Acid
     
    Raw milk in NZ
     
    ALL the Vaccines Are Contaminated – Every Last One of Them
     
    Researchers Surprised to Find Fatty Liver Disease Poses No Excess Risk for Death
     
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    Professional Dental Cleanings May Reduce Risk of Heart Attack, Stroke
     
    ScienceDaily (Nov. 13, 2011) — Professional tooth scaling was associated with fewer heart attacks and strokes in a study from Taiwan presented at the American Heart Association’s Scientific Sessions 2011.–Among more than 100,000 people, those who had their teeth scraped and cleaned (tooth scaling) by a dentist or dental hygienist had a 24 percent lower risk of heart attack and 13 percent lower risk of stroke compared to those who had never had a dental cleaning. The participants were followed for an average of seven years.—Scientists considered tooth scaling frequent if it occurred at least twice or more in two years; occasional tooth scaling was once or less in two years.–The study included more than 51,000 adults who had received at least one full or partial tooth scaling and a similar number of people matched with gender and health conditions who had no tooth scaling. None of the participants had a history of heart attack or stroke at the beginning of the study. The study didn’t adjust for heart attack and stroke risk factors — such as weight, smoking and race — that weren’t included in the Taiwan National Health insurance data base, the source of the information used in the analysis.
    “Protection from heart disease and stroke was more pronounced in participants who got tooth scaling at least once a year,” said Emily (Zu-Yin) Chen, M.D., cardiology fellow at the Veterans General Hospital in Taipei, Taiwan.–Professional tooth scaling appears to reduce inflammation-causing bacterial growth that can lead to heart disease or stroke, she said.–Hsin-Bang Leu M.D., is the study co-author. Author disclosures and funding are on the abstract.–Type of periodontal disease predicts degree of risk for heart attack, stroke, and heart failure –In a separate study, researchers found that the value of markers for gum disease predict heart attack, congestive heart failure and stroke in different ways and to different degrees.–Anders Holmlund, D.D.S., Ph.D. Centre for Research and Development of the County Council of Gävleborg, Sweden, and senior consultant; Specialized Dentistry, studied 7,999 participants with periodontal disease and found people with:-fewer than 21 teeth had a 69 percent increased risk of heart attack compared to those with the most teeth.
    A higher number of deepened periodontal pockets (infection of the gum around the base of the tooth) had a 53 percent increased risk of heart attack compared to those with the fewest pockets. The least amount of teeth had a 2.5 increased risk of congestive heart failure compared to those with the most teeth. The highest incidence of gum bleeding had a 2.1 increased risk of stroke compared to those with the lowest incidence.—
    Story Source–The above story is reprinted from materials provided by American Heart Association. –Note: Materials may be edited for content and length. For further information, please contact the source cited above.
     
    Recipe For Oral Health—take baking soda and GSE and make a paste and brush regularly –this will remove almost anything on the teeth and kill off different bacteria—and then proceed to make your own mouth wash with GSE –or peppermint essential oils –thyme E/O—Myrrh E/O—Tea Tree or Cajeput E/O –you would need a good clean drinking alcohol ( vodka-gin-grappa-tecoilla etc) add 3-5 drops in a 8 oz glass container with the alcohol—shake well or add the contents to a blender and blend at high speed for about 3-4 minutes then put into the bottle—use like a normal wash—if to strong then dilute with distilled water til you get to a strength you can handle
     
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    Enzymatic Synthesis of Pyrrolysine, the Mysterious 22nd Amino Acid
     
    PylB with methylornithin (3MO) and co-factor S-adenosylmethionine (SAM).
     
    ScienceDaily (Nov. 18, 2011) — With few exceptions, all known proteins are using only twenty amino acids. 25 years ago scientists discovered a 21st amino acid, selenocysteine and ten years ago a 22nd, the pyrrolysine. However, how the cell produces the unusual building block remained a mystery. Now researchers at the Technische Universitaet Muenchen have elucidated the structure of an important enzyme in the production of pyrrolysine.—The scientific journal Angewandte Chemie reports on their results in its “Early View” online section.
    Proteins are key players in many vital processes in living organisms.. They transport substances, catalyze chemical reactions, pump ions or recognize signaling molecules. The complexity and variety of proteins is tremendous, in the human body alone there are more than 100,000 different proteins at work. But almost all of them are made up of just twenty different amino acids. Only a few highly specialized proteins additionally contain selenocysteine, the very rare 21st amino acid discovered in 1986.—A big surprise was the discovery of a 22nd amino acid in methane-producing archaea of the family Methanosarcinaceae in 2002: pyrrolysine. It is genetically encoded in a similar manner as that of selenocysteine and the other twenty amino acids. The archaea use the unusual amino acid in proteins that they need for energy conversion. Pyrrolysine is located in the catalytic center of the proteins and is essential for their function. The energy generation process of the archaebacteria would not work without pyrrolysine.
    In March 2011, scientists at Ohio State University succeeded in deciphering parts of the manufacturing process of pyrrolysine. They proposed a reaction mechanism suggesting that the enzyme PylB catalyzes the first step of pyrrolysine biosynthesis by converting the amino acid lysine to the intermediate product metyhlornithine. Scientists headed by Michael Groll, Professor of Biochemistry at the TUM-Department of Chemistry, could now determine the crystalline structure of PylB by X-ray using structure analysis.–To their great surprise, they caught the enzyme literally “in the act”: at the time of crystallization the reaction product, methylornithine, had not left the enzyme. It adhered to a confined space, a kind of “reaction vessel,” still in connection with the centers of the enzyme responsible for its creation. “That the product was still present in the enzyme, was something special and a great stroke of luck,” says Felix Quitterer, a member of the scientific staff at the Department of Biochemistry and lead author of the publication. “We were not only able to directly detect the methylornithine, but also retroactively reconstruct how it is created from the source amino acid lysine.”—This reaction was not only unknown until now, it is also very difficult to catalyze. It is a cluster of four iron and four sulfur atoms in the active site that is the key to the conversion. “This is a really unusual enzymatic reaction. Up to now no chemist in the laboratory is able to synthesize methylornithine in a one-step reaction starting from lysine,” says Michael Groll.—The conversion of lysine to methylornithine is helping scientists to understand how archaebacteria can modify an existing system to enable the formation of a tailored amino acid that, when installed in the appropriate protein, catalyzes a very specific reaction. Researchers can use this knowledge to create artificial amino acids for “custom tailored” enzymes with special properties, that could, for example, find applications in industrial biotechnology and medicine.–A more fundamental reason for the high interest in the synthesis of the 22nd amino acid is that scientists are hoping to find new clues to the evolutionary development of the amino acid-canon. Why does the vast complexity of proteins in living organisms descend from only a few natural amino acids, even though the genetic code would be able to encode many more? An answer on this fundamental question has thus far eluded scientists. Selenocysteine and pyrrolysine are exotic exceptions, but knowledge about their development from the standard amino acids helps to come a little closer to the answer. This research was funded by the Hans-Fischer-Gesellschaft and the King Abdullah University of Science and Technology as well as the Cluster of Excellence Center for Integrated Protein Science Munich. The measurements were performed at the PXI beamline at the Paul Scherrer Institute (Villigen, Switzerland).–Story Source-The above story is reprinted from materials provided by Technische Universitaet Muenchen. Note: Materials may be edited for content and length. For further information, please contact the source cited above.–Journal Reference–Felix Quitterer, Anja List, Wolfgang Eisenreich, Adelbert Bacher, Michael Groll. Kristallstruktur der Methylornithin-Synthase (PylB): Einblicke in die Biosynthese von Pyrrolysin. Angewandte Chemie, 2011; DOI: 10.1002/ange.201106765
     
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    Raw milk in NZ
    has grown in popularity in New Zealand in recent years as more people (particularly those in cities) have become aware that raw milk from healthy, organic cows provides health benefits. Raw milk is not available for sale in supermarkets or health food stores, and as a result people in cities have been forming raw milk clubs and buying milk from farmers and sharing it with friends and family. Such raw milk clubs make raw milk accessible to city dwellers who would not otherwise have access to it, because they live too far from a supply.—Currently MAF is proposing a new regulatory system for the supply of raw milk that would make raw milk clubs illegal. MAF is also recommending restricting the amount of raw milk that any farmer can sell per day to a level that would make it uneconomic for most farmers to supply raw milk to customers.–MAF has released a discussion document and are calling for public submissions. The cut off date for submissions is December 5, 2011.
    Please visit http://www.milk.org.nz where you will find a link to the discussion document and a guide to making a submission.–The only hope to keep raw milk as an option for the vast majority of New Zealanders who live in urban areas is for a massive public response to the call for submissions, so please act now.
    Food Safety proposals for continuing to legally provide for farm gate sales of raw drinking milk-http://www.foodsafety.govt.nz/elibrary/industry/farm-gate-raw-milk-sales/index.htm
     
    FAST SUBMISSION TEMPLATE
     
    http://www.frot.co.nz/milk/submission.template.htm
     
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    ALL the Vaccines Are Contaminated – Every Last One of Them
     
    “The chief, if not the sole, cause of the monstrous increase in cancer has been vaccination” – Dr. Robert Bell, once Vice President International Society for Cancer Research at the British Cancer Hospital— (WASHINGTON, D.C.) – Have you been rushing out to get a yearly flu vaccine or diligently taking your children for the 40 or so mandated childhood vaccines?–That’s really a shame because you have unwittingly been trading a run-of-the-mill flu or just the measles, for loading up your or your children’s bodies with cancer and other deadly viruses, a destructive bacteria, a chemical selected to damage fertility, and with synthetic DNA that threatens to damage your own DNA – the biologic code for your existence.—-Who is saying the vaccines are contaminated? –None other than the (now deceased) head of vaccines at Merck, Dr. Maurice Hillerman, who on camera admitted that Merck’s Hepatitis B vaccines, contaminated with a virus, caused the AIDS epidemic in the US. He went on to say that all of Merck’s vaccines are contaminated with cancer and other viruses. (The US government has conceded the HEB B vaccine causes Lupus. That vaccine is mandated for every infant in the US on the day of birth, and is associated with MS as well.)—For Jews who have almost religiously believed in medical authorities about vaccines and poo-pooed those worried about the safety of vaccines, they might want to notice that Hillerman was Jewish.—Or they might recognize that so is Dr. Larry Palevsky, a board certified NY pediatrician, who for ten years routinely gave vaccines to his patients until he noticed them losing eye contact and then began looking into the vaccines he had blindly trusted. He found that they are ALL contaminated with viruses that are so small they can never be removed. He no longer gives any vaccines. He now treats his young patients for autism and other neurologic injuries from vaccines.
    Donald W. Scott, the editor of The Journal of Degenerative Diseases and the co-founder of the Common Cause Medical Research Foundation, links vaccines to AIDS (as did Hillerman) and to US bioweapons research, and says they are contaminated with mycoplasma, a primitive bacteria that takes apart cell walls.—Perhaps the highest scientific authority saying vaccines are contaminated is Garth Nicolson. He is a cell biologist and editor of the Journal of Clinical and Experimental Metastasis, and the Journal of Cellular Biochemistry. He is one of the most cited scientists in the world, having published over 600 medical and scientific peer-reviewed papers, edited over 14 books, and served on the editorial boards of 28 medical and scientific journals. He is not just saying that vaccines are contaminated with mycoplasma but is warning the US that they are. Nicolson goes further and says that we are all being damaged by them and contracting chronic degenerative diseases — That damage translates into lifelong patients (and thus life-long profit) for the pharmaceutical industry making the vaccines and he says doesn’t appear to be accidental. –According To CIA Statistics: As Shots Increase, U.S. Lifespan Is DECREASING–1980: 9 vaccines, autism is rare2009: 36 vaccine$ before age 5 – 2010: 55 vaccine$ before age 6 – Vaccines vs. Autism, 2009–Vaccinations before age 5-Deaths per 1000 under 5 yrs old
     
     
    According To CIA Statistics: As Shots Increase, U.S. Lifespan Is DECREASING
     
    1980: 9 vaccines, autism is rare
    2009: 36 vaccine$ before age 5
    2010: 55 vaccine$ before age 6
     
    Vaccines vs. Autism, 2009 Vaccinations before age 5 Deaths per 1000 under 5 yrs old
     
    Autism Rate Lifespan Ranking
    United States (c) 36 7.8 1 in 91 34
    Norway 13 4.4 1 in 2,000 ab 5
    Denmark 12 5.8 1 in 2,200 ab 18 d
    Japan 11 4.2 1 in 475 a 4
    Sweden 11 4.0 1 in 862 a 2
    Iceland 11 3.9 1 in 1,1000 ab 1
     
     
    All the vaccines mandated to children and many other vaccines as well, including the seasonal flu vaccines being mandated to health care workers, are contaminated with polysorbate 80, the central ingredient in a pharmaceutical industry patent to damage fertility. The pharmaceutical industry has a long history of of seeking a vaccine that would covertly sterilize whole populations So, in addition to being contaminated with cancer and other viruses, and with the bacteria mycoplasma, vaccines are intentionally “contaminated” with a chemical as well, which is, given the patent, a “patently” sought-after sterilizing agent—Beyond containing polysorbate 80 and cancer and other viruses, and likely mycoplasma, the Gardasil vaccines are contaminated in an additional way. It and all the new vaccines are contaminated with genetically engineered DNA. It can contaminate people’s DNA, just a genetically engineered crops can contaminate normal crops. Gardasil itself is contaminated with a man-made version of the HPV DNA, the very virus it was supposed to protect against, which now it threatens not only altering kids’ healthy DNA with synthetic DNA (!) but with a diseased version. —-Gardasil was suspended in India after 4 girls died but the killing has gone on in the US despite the confirmed deaths of 100 girls. and now the CDC, with special ties to Merck, its maker, wants all boys to take it, too.—Informed consent is the core of the Nuremberg Code that was created by the Nuremberg Tribunal to keep the pharmaceutical industry from ever again committing the hideous “medical” abuses it did during the Holocaust. In California, Jerry Brown is dismantling informed consent in order to get these deadly vaccines associated with infertility, into all school children. And it was during the Holocaust that the pharmaceutical experimented on Jewish women prisoners at Auschwitz to develop a vaccine that sterilized covertly. Henry Kissinger recommended the development of covertly sterilizing vaccines in a major report to the US government and as late as 2009 a Finnish Health Minister said he was behind the H1N1 vaccine that was meant to lower population.–Jerry Brown has just signed into law a bill that will allow children as young as 12 to decide whether to take a vaccine for sexually transmitted disease. Parental consent is not needed and parents will not even be allowed knowledge as to whether the child has taken the vaccine. Merck’s Hepatitis B vaccine is one that is included, as is another Merck vaccine, Gardasil, allegedly for ovarian cancer. A Gardasil researcher says there is no evidence it works. “This raises questions about the CDC’s recommendation that the series of shots be given to girls as young as 11-years old. ‘If we vaccinate 11 year olds and the protection doesn’t last… we’ve put them at harm from side effects, small but real, for no benefit,’ says Dr. Harper. ‘The benefit to public health is nothing, there is no reduction in cervical cancers … ‘ ”
     
    Current Data for Gardasil up to AUG 12, 2011
     
    Disabled 763
     
    Deaths 103
     
    Did Not Recover 4777
     
    Abnorm. Pap Smear 430
     
    Cervical Dysplasia 157
     
    Cervical Cancer 41
     
    Life Threatening 444
     
    Emergency Rm. Visit 9115
     
    Hospitalized 2307
     
    Extended Hosp. Stay 201
     
    Serious 3111
     
    Adverse Events 23388
     
    But these figures are based on statistics from medical professionals who do not wish to be sued. In reality, “less than 10% of deaths, seizures, paralysis, etc., are being reported as caused by the vaccinations that doctors gave in their office. —The following real-world estimates are based on reports from a law firm:
     
    840 young girls and 2 boys have died after receiving the Gardasil HPV Vaccine 201,010 young girls have suffered debilitating events such as fatigue, seizures, paralysis, etc. after receiving the Gardasil HPV Vaccine.
     
    The California law even approves in advance, ALL yet-to-be made (and completely untested) vaccines for sexually transmitted diseases, though of the two current Merck vaccines they are pushing on children, one Merck vaccine caused AIDS and causes Lupus and the other Merck vaccine is contaminated in multiple ways and proving highly lethal. Children will be the ones decide whether to take the vaccines, and they will make that decision after being forced to see videos of people dying terrible deaths from cancer. Not only would the vaccine be given without parental consent, but parents are denied knowledge that the vaccine is going to be given or that it was given. If the child has a seizure or dies afterwards, parents may not see their own children’s medical records.–This is what is left of the “informed consent” meant to provide human rights to protect the world from pharmaceutical industry abuses against mankind.—After World War II, it was Merck which received the flight capital of the pharmaceutical industry indicted for crimes against humanity, human enslavement and mass murder. –In the case of children, rather than their facing childhood diseases of insignificant threat, they are, by legal mandate, being bombarded repeatedly throughout their childhood with viruses that cause diseases (including cancer), a cell-destroying bacteria, a a threat to the very integrity of their DNA, and a chemical specifically chosen to impair fertility. And laws are being written to add to the already long list of vaccines they must take, including two mandated Merck vaccines. One is an old Merck vaccine that caused AIDS and is causing Lupus. The other is a Merck vaccine claiming to prevent cervical cancer though girls have little chance of contracting it in the first place (and boys, none!) and it can easily be detected by pap smear and treated successfully and there is NO evidence the vaccine prevents it. Meanwhile, it is killing children.
     
    Contamination of the polio vaccine and the continuing effects
     
    FACT: Before the Polio Vaccine, there had never been a virus from another species deliberately injected into humans.
     
    FACT: 61% of all human tumors (at autopsy) now contain the SV40 monkey virus, traceable to the Polio vaccine of the 1950s and 60s
     
    FACT: CUTTER vaccine division and WYETH produced a deadly Polio vaccine with a live virus that actually gave the recipient POLIO
    FACT: All above information was withheld from the public for years to avoid a public panic and to prevent a loss of faith in vaccines. polio was a very rare infectious disease that presented little risk to the public, but the risk was greatly exaggerated by the Polio Foundation before the introduction of the polio vaccine, the miracle vaccine – contaminated with a monkey virus which has been the cause of soft tissue cancers for decades since.
     
    Though facing no serious health risk, people are paying to have their bodies contaminated by contaminated vaccines. In taking vaccines, they are trading the minimal risk of even contracting common diseases and which themselves are rarely dangerous and can be treated if contracted – for the absolute certainty of loading their bodies with
     
    1. cancer and other infectious viruses,
     
    2. a destructive bacteria, and
     
    3. a fertility impairing chemical.
     
    They are doing this because they are being terrorized by their own government with false information on the risks of various diseases and denied critical information on the scientific risk of the vaccines.
     
    Those vaccines without a doubt threaten their own and their children’s fertility, and their very lives.
     
    ALL the Vaccines Are Contaminated – Every Last One of Them
     
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    Researchers Surprised to Find Fatty Liver Disease Poses No Excess Risk for Death
     
    ScienceDaily (Nov. 23, 2011) — Non-alcoholic fatty liver disease (NAFLD) is a common condition associated with obesity and heart disease long thought to undermine health and longevity. But a new study by Johns Hopkins researchers suggests the condition does not affect survival.
    A report on the study was published online last week in the British Medical Journal (BMJ).—“Physicians have considered fatty liver disease a really worrisome risk factor for cardiovascular disease,” says study leader Mariana Lazo, M.D., Ph.D., a postdoctoral fellow at the Johns Hopkins University School of Medicine’s Welch Center for Prevention, Epidemiology, and Clinical Research. “Our data analysis shows this doesn’t appear to be the case. We were surprised to say the least because we expected to learn by how much non-alcoholic fatty liver disease increased the risk of death and instead found the answer was not at all.”—Using health information collected from 11,371 Americans between 1994 and 1998 and followed for up to 18 years as part of the Third National Health and Nutrition Examination Survey (NHANES III), the researchers checked liver enzyme levels and ultrasound tests for evidence of NAFLD, and ultimately looked at death rates associated with NAFLD. The participants ranged in age from 20 to 74 during the data collection years. Because the ultrasounds were originally taken to assess gallbladder health, Lazo and colleagues from Johns Hopkins looked at each recording to determine the presence of fat in each person’s liver. People whose livers are 5 percent fat or more are considered to have NAFLD.–The Johns Hopkins team found no increase in mortality among those with NAFLD, which was identified in approximately 20 percent of the NHANES participants. At the end of the follow-up period, mortality from all causes was 22 percent, or 1,836 individuals. Cardiovascular disease was the cause of death for 716 participants, cancer for 480 and liver disease for 44.—Although the researchers found no increase in deaths, Lazo says further study is needed to determine whether more advanced NAFLD has serious long-term consequences for the liver, a vital organ that turns what we eat and drink into nutrients and filters harmful substances from the blood.—NAFLD, which some researchers have called the nation’s next epidemic, is characterized by the [U1]liver’s inability to break down fats and fatty build up in the organ. Found in roughly one in three Americans, it is most prevalent in those who are obese, and those with diabetes and cardiovascular disease. The spectrum of disease ranges from simple fat build-up to inflammation to the scarring and poor liver function that characterize cirrhosis. Chronic liver disease has long been associated with long-term alcohol consumption, but as the name suggests, NAFLD is found in those who are not heavy drinkers.–“We don’t yet know why mortality is not affected or whether there might be some actual protective effect of non-alcoholic fatty liver disease,” she says, “but it looks like the liver’s ability to accumulate fat may somehow shield the body from the detrimental effects of other health problems such as obesity and diabetes,” she says.-
     
    There is no treatment for NAFLD, other than lifestyle changes, including weight loss,[U2] and only a liver biopsy can determine how serious NAFLD is. Lazo says she hopes new methods are developed that more easily identify more advanced stages of NAFLD, which may not be harmless. Still, she says, her research suggests that with respect to long-term survival of people with non-alcoholic fatty liver disease, “it may not matter if you have the disease or not.” The research was supported by grants from the National Institute of Diabetes and Digestive Diseases and the American Diabetes Association.
    Other Johns Hopkins researchers involved in the study include Ruben Hernaez, M.D., Ph.D.; Susanne Bonekamp, Ph.D.; Ihab R. Kamel, M.D., Ph.D.; Frederick L. Brancati, M.D.; Eliseo Guallar, M.D., M.P.H.; and Jeanne M. Clark, M.D., M.P.H.
    Story Source-The above story is reprinted from materials provided by Johns Hopkins Medical Institutions. Note: Materials may be edited for content and length. For further information, please contact the source cited above.–
    Journal Reference-M. Lazo, R. Hernaez, S. Bonekamp, I. R. Kamel, F. L. Brancati, E. Guallar, J. M. Clark. Non-alcoholic fatty liver disease and mortality among US adults: prospective cohort study. BMJ, 2011; 343 (nov18 2): d6891 DOI: 10.1136/bmj.d6891
     
     
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    [U1]The issue here is that the foods we are eating are lacking lipase and phosphorus which can be found in fats –Saturated fats or fatty foods which would provide the system what is required to dissolve these fats—a good lipase enzyme or Sunflower or egg lecithin would assist dramatically with this—even drinking a solvent based beverage—Wine would assist with this or brandy or cognac
    [U2]This is true for just about any ailment
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    HOME
     
    Show of the Week December 16 2011
     
    New Tick-Borne Disease Discovered in Sweden
     
    U.S.-Canadian Border Deal to Streamline GMO Approval- Confirmed
     
    Experimental evidence for therapeutic potential of taurine in the treatment of nonalcoholic fatty liver disease– Recipe For NAFLD
     
    Study Evaluates Association Between Urinary Salt Excretion and Risk of Cardiovascular Events or Death
     
    Sugar-Sweetened Beverages May Increase Cardiovascular Risk in Women
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    NEW TICK-BORNE DISEASE DISCOVERED IN SWEDEN
    ScienceDaily (Dec. 6, 2011) — Researchers at the University of Gothenburg’s Sahlgrenska Academy have discovered a brand new tick-borne infection. Since the discovery, eight cases have been described around the world, three of them in the Gothenburg area, Sweden.—In July 2009 a 77-year-old man from western Sweden was out kayaking when he went down with acute diarrhea, fever and temporary loss of consciousness. He was taken to hospital where it was found that he was also suffering with deep vein thrombosis (DVT). Following treatment with antibiotics, he was discharged some days later with an anticoagulant to thin his blood. However, the man — who had an impaired immune system — went down with a fever again.—-Brand new infection—-Over the following months the 77-year-old was admitted as an emergency case on several occasions, but despite repeated attempts to find a microbe, and repeated doses of antibiotics, the fever returned. Finally the patient’s blood underwent special analysis to look for bacterial DNA — and that produced results. The findings matched a bacterium in an online gene bank and the results were a sensation: the man had contracted a brand new infection in humans which had never been described in the world before.—-Never before seen in Sweden– The man’s blood contained DNA that derived with 100% certainty from the bacterium Neoehrlichia mikurensis. This bacterium was identified for the first time in Japan in 2004 in rats and ticks but had never before been seen in Sweden in ticks, rodents or humans.—Christine Wennerås, a doctor and researcher at the Department of Infectious Diseases and the Department of Haematology and Coagulation at the University of Gothenburg’s Sahlgrenska Academy, has been studying the case since it first came to light. Last year she was able, for the first time, to describe the newly discovered disease in a scientific article published in the Journal of Clinical Microbiology.—“Since our discovery the bacterium has been reported in eight cases around the world, three of them in Gothenburg,” says Wennerås.—-Causes DVT—All three of the Gothenburg cases involved patients with an impaired immune system, all of whom became ill during the summer months when ticks are most active.—“The nasty thing about this infection is that it causes DVT, at least in people with an impaired immune system,” says Wennerås. “This can be life-threatening. Fortunately, the infection can be treated successfully with antibiotics.—Spreads from mammals-“If the newly discovered bacterium is similar to those we already know, it has presumably spread from wild mammals to people via ticks, and it is unlikely that it can be passed on from person to person.”[U1] The mikurensis in the bacterium’s name comes from the Japanese island of Mikura, where it was first discovered. Story Source–The above story is reprinted from materials provided by University of Gothenburg.—Personal Note: this sounds familiar to the black plague of the past—
     
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    U.S.-Canadian Border Deal to Streamline GMO Approval- Confirmed
     
    Canada-U.S. Regulatory Co-operation Council under border deal coverage would put Canada under draconian Food Safety Modernization Act, fast track GMO approval.
     
    AARON DYKES– INFOWARS.COM
    OUR REPORT SOUNDING THE ALARM THAT OBAMA AND HARPER’S SECRETIVE BORDER DEAL, DUE TO BE SIGNED NEXT WEEK, WOULD BE USED TO FAST TRACK GMO ACCEPTANCE HAS BEEN CONFIRMED. THE DETAILS HAVE BEEN KEPT UNDER WRAPS, BUT RECENT REPORTS REVEALED THAT THE ‘BEYOND BORDERS’ SECURITY AND LAW ENFORCEMENT DEAL WOULD ALSO SEEK TO ‘HARMONIZE’ U.S. AND CANADIAN REGULATORY STANDARDS FOR FOOD, AUTO AND OTHER TRADE SECTORS.—The Globe and Mail confirms that the North American Union security perimeter initiative, sold to the public as new security measures at the border, has a second major component– the Canada-U.S. Regulatory Co-operation Council.—-Mr. Harper… said there are two issues on the joint security and economic agenda of the two countries. One, he said, is the border and perimeter initiative, and the other is Canada-U.S. Regulatory Co-operation Council.–“WE ARE SEEKING WAYS OF ENSURING SECURITY IN NORTH AMERICA WHILE AT THE SAME TIME MAKING SURE THAT WE CONTINUE STRONG CANADIAN ACCESS TO THE AMERICAN MARKET,” MR. HARPER TOLD REPORTERS.–This will encompass far more than just the terms under which food can cross the border– it will put approval for biotechnology on a fast track in both countries and impose FDA and other regulations on both countries.—THE AGENDA OF THE CANADA-U.S. REGULATORY CO-OPERATION COUNCIL WAS QUIETLY ANNOUNCED IN FEBRUARY 2011, PUTTING EXPLICIT FOCUS ON THE IMPLEMENTATION OF THE U.S. FOOD SAFETY MODERNIZATION ACT REQUIREMENTS UNDER THE LARGER PERIMETER SECURITY AND ECONOMIC COMPETITIVENESS AGENDA. THAT NIGHTMARISH LEGISLATION WAS HEAVILY CRITICIZED FOR NEW AUTHORITY IT GRANTS THE U.S. GOVERNMENT OVER THE RIGHT TO GROW, TRADE AND TRANSPORT FOODS OF ANY KIND.
     
    In other words, it is poised to boost the reach of Big Agra and biotech firms at the expense of small farmers and ordinary people.—Now, under the new Obama-Harper deal, Canada, too, would accept this tyranny over food.
    SPECIFICALLY, THE CANADA-U.S. REGULATORY COOPERATIVE COUNCIL (UNDER “FREE” TRADE) WOULD ESTABLISH A JOINT REVIEW PROCESS FOR PRE-MARKET GMO APPROVAL, ESTABLISH A POLICY FOR THE ACCEPTANCE AND EXPORT OF LLPS (LOW-LEVEL PRESENCE CONTAMINATION OF GENETICALLY MODIFIED FOODS BANS IN COUNTRY OF EXPORT) AND RECOMMENDS ELIMINATING MANDATORY COUNTRY OF ORIGIN LABELING, AND MORE.
     
    From the report–Biotechnology
     
    Establish a joint review process or a Mutual Recognition Agreement for biotechnology product approvals to facilitate synchronized approvals.—Establish a common policy for dealing with low level presence (LLP) of unapproved biotechnology products (e.g., harmonized risk assessments and acceptance of LLP already commercially available in the other country).
     
    A 2004 SYMPOSIUM ON CANADA-U.S. REGULATORY CO-OPERATION EVEN RECOMMENDS OUTRIGHT ACCEPTANCE OF U.S. FOOD STANDARDS: THE HEALTH PRODUCTS AND FOOD BRANCH IS NOW CONSIDERING A RISK-BASED APPROACH TO REGULATORY CO-OPERATION, WHICH MIGHT ENTAIL ACCEPTING OR REFERENCING DECISIONS MADE BY THE US FOOD AND DRUG ADMINISTRATION AND OTHER REGULATORS FOR LOW-RISK PRODUCTS.—With U.S. regulatory agencies filled with revolving door stooges like FDA Deputy Commissioner for Foods Michael R. Taylor, formerly a Vice President at Monsanto and long a go-between for biotech and government regulations, there is little doubt what direction such a “harmonization” of food regulations, including FDA recommendations, would mean under the ‘Beyond Borders’ deal.
     
    President Obama and Prime Minister Stephen Harper are scheduled to meet one-on-one next Wednesday to discuss and sign the deal… then its details will finally be revealed to the world.—-Perimeter Security and Economic Competitiveness: Regulatory Cooperation – A Report on the Consultations on Regulatory Cooperation Between Canada and the United States
     
    Read PDF here or web version here. Excerpt from p. 25
     
    APPENDIX 2: SPECIFIC PROPOSALS BY SECTOR-AGRICULTURE AND FOOD- FOOD SAFETY SYSTEMS—Develop common approaches to food safety requirements and policies, aligning new regulations and guidance—specifically, implementation of the U.S. Food Safety Modernization Act requirements.—Mutually recognize food safety systems.—Improve the effectiveness of meat-safety-system equivalency agreements (i.e., eliminate or minimize re-inspections of product and microbial testing at the border).–ACCEPT INDUSTRY-LED STANDARDS AND PROGRAMS THAT ARE BASED ON INTERNATIONAL STANDARDS (E.G., THE HAZARD ANALYSIS CRITICAL CONTROL POINT, OR HACCP).—HARMONIZE APPROVALS FOR FOOD-SAFETY-ENHANCING PRODUCTS AND TECHNOLOGY USED IN PROCESSING (E.G., PACKAGING MATERIALS, ANTI-MICROBIAL INTERVENTIONS, TESTING METHODOLOGIES AND PROCESSES, SANITATION, AND MAINTENANCE CHEMICALS AND EQUIPMENT).—BIOTECHNOLOGY—ESTABLISH A JOINT REVIEW PROCESS OR A MUTUAL RECOGNITION AGREEMENT FOR BIOTECHNOLOGY PRODUCT APPROVALS TO FACILITATE SYNCHRONIZED APPROVALS.—ESTABLISH A COMMON POLICY FOR DEALING WITH LOW LEVEL PRESENCE (LLP) OF UNAPPROVED BIOTECHNOLOGY PRODUCTS (E.G., HARMONIZED RISK ASSESSMENTS AND ACCEPTANCE OF LLP ALREADY COMMERCIALLY AVAILABLE IN THE OTHER COUNTRY).
    AGRICULTURAL INPUTS
     
    BUILDING ON SIGNIFICANT COLLABORATION TO DATE, ALIGN PRE-MARKET APPROVAL PROCESSES AND DATA REQUIREMENTS FOR CROP PROTECTION PRODUCTS (I.E., PESTICIDES, SEED TREATMENTS) TO FACILITATE JOINT REVIEWS AND ASSESSMENTS AND IMPROVE RE-EVALUATION AND RE-REGISTRATION PROCESSES.
     
    RESOLVE DISCREPANCIES IN MAXIMUM RESIDUE LIMITS FOR CROP PROTECTION PRODUCTS.—MODIFY THE U.S. ENVIRONMENTAL PROTECTION AGENCY (EPA) NOTICE-OF-ARRIVAL PROCESS TO REMOVE THE ADVANCE NOTIFICATION REQUIREMENT FOR PRODUCTS THAT ARE ALREADY EPA-REGISTERED.—-HARMONIZE THE APPROVAL PROCESS FOR VETERINARY DRUGS, INCLUDING THE ESTABLISHMENT OF MAXIMUM RESIDUE LIMITS.—LABELLING, PACKAGING AND PRODUCT CONTENT—ALIGN NUTRITIONAL LABELLING FORMATS AND CONTENT (E.G., NUTRIENT DEFINITIONS, REQUIRED VALUES, DAILY RECOMMENDED INTAKES).–HARMONIZE APPROACHES TO ALLOWED HEALTH CLAIMS.-ALIGN STANDARDS FOR DISCRETIONARY FORTIFICATION OF FOODS.DEVELOP UNIFORM LABELLING REQUIREMENTS (E.G., QUALITY SPECIFICATIONS, METHOD OF PRODUCTION CLAIMS, GLYCEMIC INDEX LABELLING).–ADOPT A COMMON APPROACH TO THE NOMENCLATURE OF MEAT CUTS.–ELIMINATE OR AMEND U.S. MANDATORY COUNTRY-OF-ORIGIN LABELLING REQUIREMENTS.—-ALIGN CONTAINER SIZE REQUIREMENTS (INFANT FOOD, BOTTLED AND CANNED GOODS).[U2]
     
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    Experimental evidence for therapeutic potential of taurine in the treatment of nonalcoholic fatty liver disease
    Christopher L. Gentile1,*, Angela M. Nivala1,*, Jon C. Gonzales1, Kyle T. Pfaffenbach1, Dong Wang1, Yuren Wei1, Hua Jiang2, David J. Orlicky3, Dennis R. Petersen4, Michael J. Pagliassotti1, and Kenneth N. Maclean2
     
    The incidence of obesity is now at epidemic proportions and has resulted in the emergence of nonalcoholic fatty liver disease (NAFLD) as a common metabolic disorder that can lead to liver injury and cirrhosis. Excess sucrose and long-chain saturated fatty acids in the diet may play a role in the development and progression of NAFLD. One factor linking sucrose and saturated fatty acids to liver damage is dysfunction of the endoplasmic reticulum (ER). Although there is currently no proven, effective therapy for NAFLD, the amino sulfonic acid taurine is protective against various metabolic disturbances, including alcohol-induced liver damage. The present study was undertaken to evaluate the therapeutic potential of taurine to serve as a preventative treatment for diet-induced NAFLD. We report that taurine significantly mitigated palmitate-mediated caspase-3 activity, cell death, ER stress, and oxidative stress in H4IIE liver cells and primary hepatocytes. In rats fed a high-sucrose diet, dietary taurine supplementation significantly reduced hepatic lipid accumulation, liver injury, inflammation, plasma triglycerides, and insulin levels. The high-sucrose diet resulted in an induction of multiple components of the unfolded protein response in the liver consistent with ER stress, which was ameliorated by taurine supplementation. Treatment of mice with the ER stress-inducing agent tunicamycin resulted in liver injury, unfolded protein response induction, and hepatic lipid accumulation that was significantly ameliorated by dietary supplementation with taurine. Our results indicate that dietary supplementation with taurine offers significant potential as a preventative treatment for NAFLD.
     
    Recipe For NAFLD—take Taurine and add it to black coffee to assist the liver to remove the excesses that will develop—this will reduce the fat build up as well as regulate the glycose and protect the liver from cancers and other pathogens— use 500mgs -1000mgs in a black cup of coffee
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    Study Evaluates Association Between Urinary Salt Excretion and Risk of Cardiovascular Events or Death
     
    ScienceDaily (Nov. 22, 2011) — For persons with cardiovascular disease or diabetes, urinary sodium excretion (a surrogate for salt intake) at higher levels or at lower levels compared to mid-range values was associated with an increased risk of cardiovascular events (for higher levels) or cardiovascular death and hospitalization for congestive heart failure (for lower levels), according to a study in the Nov. 23/30 issue of JAMA. Also, higher estimated urinary potassium excretion was associated with a reduced risk of stroke.—There is uncertainty regarding the optimal daily intake of sodium. Findings from prospective cohort studies, evaluating the association between sodium intake and cardiovascular (CV) events, have been conflicting. “Clarifying the optimal daily intake of sodium is particularly important in patients with established CV disease, where it has been inadequately studied. Patients with CV disease may be especially vulnerable to the CV effects of high and low sodium intake and are most likely to receive recommendations on restricting sodium intake,” according to background information in the article. The authors add that the optimal level of daily potassium intake, a proposed modifier of the association between sodium intake and CV disease, has not been established.- Martin J. O’Donnell, M.B., Ph.D., of McMaster University, Hamilton, Ontario, Canada, and colleagues examined the association between sodium and potassium excretion (markers of intake) and CV events and mortality. The study consisted of an observational analyses of 2 cohorts (n = 28,880) included in the ON TARGET and TRANSCEND trials (November 2001-March 2008 from initial recruitment to final follow-up). The researchers estimated 24-hour urinary sodium and potassium excretion from a morning fasting urine sample. Multivariable models were used to determine the association of urinary sodium and potassium with CV events (myocardial infarction [MI; heart attack], stroke, and hospitalization for congestive heart failure (CHF) and mortality.
    At study entry, the average estimated 24-hour excretion for sodium was 4.77 g and 2.19 g for potassium. After a median (midpoint) follow-up of 56 months, the composite outcome occurred in 4,729 (16.4 percent) participants. The researchers found that after multivariable analysis, compared with baseline sodium excretion of 4 to 5.99 g per day (n = 14,156 [15.2 percent with the composite outcome]), higher baseline sodium excretion (18.4 percent for 7-8 g/d and 24.1 percent for greater than 8 g/d) and lower sodium excretion (18.2 percent for 2-2.99 g/d and 20.2 percent for less than 2g/d) were associated with an increased risk of the composite of CV death, heart attack, stroke, and hospitalization for CHF.—Compared with the reference group, higher baseline sodium excretion was associated with an increased risk of CV death (9.7 percent for 7-8 g/day; and 11.2 percent for greater than 8 g/day), MI (6.8 percent for greater than 8 g/day), stroke (6.6 percent for greater than 8 g/day), and hospitalization for CHF (6.5 percent for greater than 8 g/day). Lower sodium excretion was associated with an increased risk of CV death (8.6 percent for 2-2.99 g/day; 10.6 percent for less than 2 g/day), and hospitalization for CHF (5.2 percent for 2-2.99 g/day) on multivariable analysis. Compared with an estimated potassium excretion of less than 1.5 g per day, higher potassium excretion was associated with a reduced risk of stroke on multivariable analysis.—The researchers note that previous individual prospective cohort studies have either reported a positive association, no association, or an inverse relationship between sodium intake and CV mortality. “Discrepant findings of previous studies are likely due to differences in ranges of sodium intake, study populations, methods of measurement, and failure to explore a nonlinear association.”–“Compared with moderate sodium excretion, we found an association between high sodium excretion and CV events and low sodium excretion and CV death and hospitalization for CHF, which emphasizes the urgent need to establish a safe range for sodium intake in randomized controlled trials. Higher urinary potassium excretion was associated with lower stroke risk and is a potential intervention that merits further evaluation for stroke prevention.”—-Editorial: Urinary Sodium and Cardiovascular Disease Risk
    In an accompanying editorial, Paul K. Whelton, M.B., M.D., M.Sc., of the Tulane University School of Public Health and Tropical Medicine, New Orleans, comments on the importance of reducing salt intake.—“Most U.S. adults consume levels of sodium far in excess of physiologic need, and the vast majority of that excess is added during the processing of foods. A progressive reduction in the addition of sodium to food products could represent one of the ‘lifestyle’ changes with the greatest potential for intervention success. This shift to a more natural diet would concurrently lead to an absolute increase in dietary potassium content and also lead to an improved sodium-potassium ratio, which may be more desirable than change of either electrolyte on its own. The scientific underpinning for the health benefits from sodium reduction is strong, and the available evidence does not support deviating from the stated goal of reducing the exposure to dietary sodium in the general population.” Story Source–The above story is reprinted from materials provided by JAMA and Archives Journals. –Journal References-M. J. O’Donnell, S. Yusuf, A. Mente, P. Gao, J. F. Mann, K. Teo, M. McQueen, P. Sleight, A. M. Sharma, A. Dans, J. Probstfield, R. E. Schmieder. Urinary Sodium and Potassium Excretion and Risk of Cardiovascular Events. JAMA: The Journal of the American Medical Association, 2011; 306 (20): 2229 DOI: 10.1001/jama.2011.1729 P. K. Whelton. Urinary Sodium and Cardiovascular Disease Risk: Informing Guidelines for Sodium Consumption. JAMA: The Journal of the American Medical Association, 2011; 306 (20): 2262 DOI: 10.1001/jama.2011.1746
     
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    Sugar-Sweetened Beverages May Increase Cardiovascular Risk in Women
     
    ScienceDaily (Nov. 13, 2011) — Drinking two or more sugar-sweetened beverages a day may expand a woman’s waistline and increase her risk of heart disease and diabetes, according to research presented at the American Heart Association’s Scientific Sessions 2011.—In this study, researchers compared middle-aged and older women who drank two or more sugar-sweetened beverages a day, such as carbonated sodas or flavored waters with added sugar, to women who drank one or less daily. Women consuming two or more beverages per day were nearly four times as likely to develop high triglycerides, and were significantly more likely to increase their waist sizes and to develop impaired fasting glucose levels. The same associations were not observed in men.–“Women who drank more than two sugar-sweetened drinks a day had increasing waist sizes, but weren’t necessarily gaining weight[U3],” said Christina Shay, Ph.D., lead author of the study and assistant professor at the University of Oklahoma Health Sciences Center in Oklahoma City. “These women also developed high triglycerides and women with normal blood glucose levels more frequently went from having a low risk to a high risk of developing diabetes over time.”—-The Multi-Ethnic Study of Atherosclerosis (MESA) included food frequency surveys in 4,166 African-American, Caucasian, Chinese-Americans and Hispanic adults 45 to 84 years old. At the beginning of the study the participants didn’t have cardiovascular disease.–Researchers assessed risk factors in three follow-up exams spanning five years starting in 2002. Participants were monitored for weight gain, increases in waist circumference, low levels of high density lipoproteins (HDL “good” cholesterol), high levels of low density lipoproteins (LDL “bad” cholesterol), high triglycerides, impaired fasting glucose levels, and type 2 diabetes.—-“Most people assume that individuals who consume a lot of sugar-sweetened drinks have an increase in obesity, which in turn, increases their risk for heart disease and diabetes,” said Shay, formerly of Northwestern University’s Department of Preventive Medicine in Chicago, where the study was conducted. “Although this does occur, this study showed that risk factors for heart disease and stroke developed even when the women didn’t gain weight.”–Women may have a greater chance for developing cardiovascular disease risk factors from sugar-sweetened drinks because they require fewer calories than men which makes each calorie count more towards cardiovascular risk in women, Shay said.—Researchers have yet to determine exactly how sugar-sweetened beverages influence cardiovascular risk factors such as high triglycerides in individuals who do not gain weight, Shay said, but further work is planned to try and figure that out.–Co-authors include Jennifer A. Nettleton, Ph.D.; Pamela L. Lutsey, Ph.D., M.P.H.; Tamar S. Polonsky, M.D.; Mercedes R. Carnethon, Ph.D.; Cheeling Chan, M.S.; Linda Van Horn, Ph.D., R.D.; and Gregory Burke, M.D.–The National Heart, Lung, and Blood Institute funded the study.–Story Source-The above story is reprinted from materials provided by American Heart Association.
     
    TOP E
    [U1]Not sure how they can make these statements—since it has already jumped from different species
    [U2]Metric is comin to the usa in everything
    [U3]Sounds like inflammatory reaction to the pancreas and colon and potentially the liver
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    TOP F
    HOME
     
    Show of the Week December 19 2011
     
    In Third-Degree Burn Treatment, Hydrogel Helps Grow New Scar-Free Skin
     
    Antioxidant Has Potential in the Alzheimer’s Fight
     
    Feds Admit to Purposely Infecting People
     
    Ark. Court Affirms $50M Verdict for Rice Farmers
     
    Catch the Fever- It’ll Help You Fight Off Infection, Evidence Shows
     
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    In Third-Degree Burn Treatment, Hydrogel Helps Grow New Scar-Free Skin
     
    Guoming Sun, a postdoctoral fellow, and Sharon Gerecht, an assistant professor of chemical and biomolecular engineering, helped develop a hydrogel that improved burn healing in early experiments.
     
    ScienceDaily (Dec. 13, 2011) — Johns Hopkins researchers have developed a jelly-like material and wound treatment method that, in early experiments on skin damaged by severe burns, appeared to regenerate healthy, scar-free tissue.—In the Dec. 12-16 online Early Edition of Proceedings of the National Academy of Sciences, the researchers reported their promising results from mouse tissue tests. The new treatment has not yet been tested on human patients. But the researchers say the procedure, which promotes the formation of new blood vessels and skin, including hair follicles, could lead to greatly improved healing for injured soldiers, home fire victims and other people with third-degree burns.—The treatment involved a simple wound dressing that included a specially designed hydrogel — a water-based, three-dimensional framework of polymers. This material was developed by researchers at Johns Hopkins’ Whiting School of Engineering, working with clinicians at the Johns Hopkins Bayview Medical Center Burn Center and the Department of Pathology at the university’s School of Medicine.—Third-degree burns typically destroy the top layers of skin down to the muscle. They require complex medical care and leave behind ugly scarring. But in the journal article, the Johns Hopkins team reported that their hydrogel method yielded better results. “This treatment promoted the development of new blood vessels and the regeneration of complex layers of skin, including hair follicles and the glands that produce skin oil,” said Sharon Gerecht, an assistant professor of chemical and biomolecular engineering who was principal investigator on the study.—Gerecht said the hydrogel could form the basis of an inexpensive burn wound treatment that works better than currently available clinical therapies, adding that it would be easy to manufacture on a large scale. Gerecht suggested that because the hydrogel contains no drugs or biological components to make it work, the Food and Drug Administration would most likely to classify it as a device. Further animal testing is planned before trials on human patients begin. But Gerecht said, “It could be approved for clinical use after just a few years of testing.”—John Harmon, a professor of surgery at the Johns Hopkins School of Medicine and director of surgical research at Bayview, described the mouse study results as “absolutely remarkable. We got complete skin regeneration, which never happens in typical burn wound treatment.”—If the treatment succeeds in human patients, it could address a serious form of injury. Harmon, a coauthor of the PNAS journal article, pointed out that 100,000 third-degree burns are treated in U. S. burn centers like Bayview every year. A burn wound dressing using the new hydrogel could have enormous potential for use in applications beyond common burns, including treatment of diabetic patients with foot ulcers, Harmon said.–Guoming Sun, Gerecht’s Maryland Stem Cell Research Postdoctoral Fellow and lead author on the paper, has been working with these hydrogels for the last three years, developing ways to improve the growth of blood vessels, a process called angiogenesis. “Our goal was to induce the growth of functional new blood vessels within the hydrogel to treat wounds and ischemic disease, which reduces blood flow to organs like the heart,” Sun said. “These tests on burn injuries just proved its potential.”—Gerecht says the hydrogel is constructed in such a way that it allows tissue regeneration and blood vessel formation to occur very quickly. “Inflammatory cells are able to easily penetrate and degrade the hydrogel, enabling blood vessels to fill in and support wound healing and the growth of new tissue,” she said. For burns, the faster this process occurs, Gerecht added, the less there is a chance for scarring.—Originally, her team intended to load the gel with stem cells and infuse it with growth factors to trigger and direct the tissue development. Instead, they tested the gel alone. “We were surprised to see such complete regeneration in the absence of any added biological signals,” Gerecht said.—Sun added, “Complete skin regeneration is desired for various wound injuries. With further fine-tuning of these kinds of biomaterial frameworks, we may restore normal skin structures for other injuries such as skin ulcers.”–Gerecht and Harmon say they don’t fully understand how the hydrogel dressing is working. After it is applied, the tissue progresses through the various stages of wound repair, Gerecht said. After 21 days, the gel has been harmlessly absorbed, and the tissue continues to return to the appearance of normal skin.—The hydrogel is mainly made of water with dissolved dextran — a polysaccharide (sugar molecule chains). “It also could be that the physical structure of the hydrogel guides the repair,” Gerecht said. Harmon speculates that the hydrogel may recruit circulating bone marrow stem cells in the bloodstream. Stem cells are special cells that can grow into practically any sort of tissue if provided with the right chemical cue. “It’s possible the gel is somehow signaling the stem cells to become new skin and blood vessels,” Harmon said.–Additional co-authors of the study included Charles Steenbergen, a professor in the Department of Pathology; Karen Fox-Talbot, a senior research specialist from the Johns Hopkins School of Medicine; and physician researchers Xianjie Zhang, Raul Sebastian and Maura Reinblatt from the Department of Surgery and Hendrix Burn and Wound Lab. From the Whiting School’s Department of Chemical and Biomolecular Engineering, other co-authors were doctoral students Yu-I (Tom) Shen and Laura Dickinson, who is a Johns Hopkins Institute for NanoBioTechnology (INBT) National Science Foundation IGERT fellow. Gerecht is an affiliated faculty member of INBT.—The work was funded in part by the Maryland Stem Cell Research Fund Exploratory Grant and Postdoctoral Fellowship and the National Institutes of Health.—The Johns Hopkins Technology Transfer staff has filed a provisional patent application to protect the intellectual property involved in this project.–Story Source-The above story is reprinted from materials provided by Johns Hopkins University.
     
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    Antioxidant Has Potential in the Alzheimer’s Fight
     
    ScienceDaily (Dec. 14, 2011) — When you cut an apple and leave it out, it turns brown. Squeeze the apple with lemon juice, an antioxidant, and the process slows down.—Simply put, that same “browning” process-known as oxidative stress-happens in the brain as Alzheimer’s disease sets in. The underlying cause is believed to be improper processing of a protein associated with the creation of free radicals that cause oxidative stress.—Now, a study by researchers in the University of Georgia College of Pharmacy has shown that an antioxidant can delay the onset of all the indicators of Alzheimer’s disease, including cognitive decline. The researchers administered an antioxidant compound called MitoQ to mice genetically engineered to develop Alzheimer’s. The results of their study were published in the Nov. 2 issue of the Journal of Neuroscience.—Oxidative stress is believed to cause neurons in the brain to die, resulting in Alzheimer’s. Study author James Franklin, an associate professor of pharmaceutical and biomedical sciences, has studied neuronal cell death and oxidative stress at UGA since 2004.—“The brain consumes 20 percent of the oxygen in the body even though it only makes up 5 percent of the volume, so it’s particularly susceptible to oxidative stress,” said Franklin, coauthor of the study along with Meagan McManus, who received her Ph.D. in neuroscience from UGA in 2010.–The UGA researchers hypothesized that antioxidants administered unsuccessfully by other researchers to treat Alzheimer’s were not concentrated enough in the mitochondria of cells. Mitochondria are structures within cells that have many functions, including producing oxidative molecules that damage the brain and cause cell death.—“MitoQ selectively accumulates in the mitochondria,” said McManus, who is now studying mitochondrial genetics and dysfunction as a postdoctoral researcher at Children’s Hospital of Philadelphia. “It is more effective for the treatment to go straight to the mitochondria, rather than being present in the cell in general,” she said. –In their study, mice engineered to carry three genes associated with familial Alzheimer’s were tested for cognitive impairment using the Morris Water Maze, a common test for memory retention. The mice that had received MitoQ in their drinking water performed significantly better than those that didn’t. Additionally, the treated mice tested negative for the oxidative stress, amyloid burden, neural death and synaptic loss associated with Alzheimer’s. Story Source–The above story is reprinted from materials provided by University of Georgia. The original article was written by Chelsea Toledo.—
     
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    Feds Admit to Purposely Infecting People
     
    August 31, 2011. Washington. Most Americans will never hear about the secret medical experiments done on unsuspecting humans by their government. Even though there are dozens, if not hundreds of known secret programs, until the government admits to the sinister crimes, the media and most people refuse to accept the fact that their own government routinely carries out such horrendous acts. That was the case Monday when a Presidential Commission released their findings of yet another secret government program.–According to the Presidential Commission for the Study of Bioethical Issues, from 1946 to 1948, the US government paid the government in Guatemala to allow American doctors to purposely and secretly infect certain segments of the Guatemalan population with sexually transmitted diseases, some of them deadly. According to the report, “U.S. public health officers wanted to learn more about ways of treating these diseases.” Also according to the findings, researchers targeted people with little or no voice in society or those accustomed to obeying orders without question. Specifically, victims of the secret program centered around mental patients, prisoners, commercial sex workers, and members of the Guatemalan army.—Commenting on the conspiracy theory that turned out to be real, Director of the US Military HIV Research Program, Dr. Nelson L. Michael said, “There was no value. What stings the most in terms of bad science is that it never passed peer review and was never published.” Presidential Commission member Anita Allen told Associated Press, “The researchers put their own medical advancement first and human decency a far second.”—The secret program was funded by the US Federal government and attempted to measure the effectiveness of new antibiotics. This particular program not only infected hundreds of unsuspecting Guatemalans, but also Americans. Prisoners in the Terra Haute, Indiana prison system were also purposely infected with diseases like gonorrhea, syphilis and chancroid. Unlike the unknowing Guatemalans, the prisoners in the US were made aware of the deliberate infections beforehand.
    For decades, the US Federal government successfully covered up the secret experiments. Last year however, researchers at Wellesley College discovered documents detailing the experiment from the program’s lead scientist Dr. John Cutler.–Some of the specific examples from the program detailed by Associated Press include seven women afflicted with epilepsy. They were injected at the base of the skull with syphilis. US scientists thought syphilis might turn out to be a cure for epilepsy. As a result, each of the women became infected with bacterial meningitis.
    In another example, an unsuspecting female subject was infected with syphilis. US researchers were curious to see the effects of a second, additional infection of gonorrhea. Doctors proceeded to purposely infect the woman with gonorrhea in numerous parts of her body, including her eyes. Within six months, the woman was dead. In all, more than 83 people are known to have perished during or immediately after the experiments. With the admittedly poor record keeping, officials concede the death toll could be much, much higher. Guatemalan officials are carrying out their own investigation and hope to reveal more details.—While most Americans are in blissful denial that their government could be guilty of such atrocious acts, their government continues it’s never- ending quest to quell any knowledge of the hundreds of secret government programs that purposely and secretly infected people with diseases. In one case after another, government officials have had to admit to carrying out such horrid medical experiments. Most examples sound like they came out of the Nazi trials in Nuremberg rather than United States.—The fact is, secret government experiments that infect unsuspecting Americans with deadly diseases is nothing new. In fact, most argue that it’s still going on today. Records continue to be discovered showing that using Americans as unknowing guinea pigs in secret medical experiments is an accepted practice that’s been continuously occurring for over 80 years.—Read the Whiteout Press Special Report, ‘Secret Government Experiments on the American People’ for examples of dozens of secret programs beginning in 1931 and continuing through today. Most recently, 88 members of Congress signed a letter demanding more information regarding Gulf War Syndrome and the details of how tens of thousands of US military personnel, as well as their spouses and future unborn children, could be infected with biological weapons and Gulf War Syndrome.—Government officials led by then President George HW Bush refused to acknowledge Gulf War Syndrome as anything more than a made-up disease that didn’t really exist. It wasn’t until a staggering number of newborn babies born to Gulf War vets were being diagnosed with dozens of strange and rare medical conditions, all directly related to exposure to weapons grade biological agents. Scientists and investigators have so far documented that the secret biological weapons used during the Gulf War were manufactured in Houston, TX and Boca Raton, FL. In the process, researchers also discovered another secret laboratory experiment on unsuspecting Americans. These particular biological weapons were tested on prisoners in the Texas Department of Corrections.—With Congress still fighting for confirmation more than 15 years later, perhaps someday Americans will learn what kind of secret medical experiments their government is performing on them today without their knowledge or consent. If history proves one thing, it’s that these sinister secretive medical experiments have been continuously carried out by the US government without pause since 1931 and there is absolutely no reason to believe they’re not still going on today.
     
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    Ark. Court Affirms $50M Verdict for Rice Farmers
    The Arkansas Supreme Court on Thursday affirmed a nearly $50 million verdict for farmers who say they lost money because a company’s genetically altered rice seeds contaminated the food supply and drove down crop prices. Bayer, the German conglomerate whose Bayer CropScience subsidiary produced the seeds, had argued that Arkansas tort laws set a limit on punitive damages and that courts should set aside jury awards that “shock the conscience.” In the April 2010 verdict, a Lonoke County jury awarded $42 million in punitive damages and $5.9 million in actual damages. But in its 24-page opinion released Thursday, the state Supreme Court agreed with the lower court that the cap on punitive damages was unconstitutional. Associate Justice Courtney Hudson Goodson wrote that the cap “limits the amount of recovery outside the employment relationship,” while the Arkansas constitution only allows limits on compensation paid by employers to employees. The latest decision comes years after Bayer developed an experimental strain of rice called LibertyLink to withstand its Liberty herbicide. Federal regulators had not yet approved it for human consumption when trace amounts were found mixed with conventional rice seed in storage bins in Arkansas and Missouri. No human health problems have been associated with the contamination, but that wasn’t known at the time. The fear that the rice was unsafe, along with the notion that genetically altered rice was somehow impure, quashed sales in major markets. Rice futures plummeted by $150 million immediately after the contamination announcement. European nations quit accepting shipments of rice from the U.S. that hadn’t been extensively tested to show they weren’t contaminated. Japan banned all American rice. Growers in Arkansas — where about half of the nation’s rice is produced — as well as California, Louisiana, Mississippi, Missouri and Texas sued Bayer, claiming rice prices fell so severely that they received much less for their crops. Bayer argued that any damages were minimal and short-term. This case is only about economic losses,” Bayer’s attorneys argued in a court document filed in Arkansas this year. “Mixing conventional rice with less valuable (LibertyLink rice) did not constitute ‘physical’ damage to the rice (as seed or as crop), the land, the farming implements or anything else.” Bayer CropScience announced in July that it would pay up to $750 million to settle claims, including those from farmers who say they had to plant different crops and made less money from them. The farmers in the Lonoke County suit cannot receive money from that $750 million pot. The Lonoke County farmers argued that Bayer knew of the contamination as early as January 2006, before that year’s crops were sowed, and was thus not only negligent in its handling of LibertyLink rice but acted with malicious intent by not announcing the contamination as soon as it learned about it. Lawyers for the farmers said their clients didn’t learn of the contamination until the USDA’s announcement in August 2006, when it was almost time to harvest that year’s crops. The company said it notified the government as soon as it discovered LibertyLink had shown up in commercial rice. The lawsuit and settlement apply to long-grain rice, the kind used in pilaf or typically mixed with beans. They don’t affect farmers who planted medium-grain rice, which is often used in sushi, or short-grain rice, which is often used to make cereal. Thursday’s decision calling the cap on punitive damages unconstitutional drew sharp criticism from the Arkansas State Chamber of Commerce, a pro-industry interest group, which said the ruling would allow judges and juries to punish businesses without limit. This will have a chilling effect on the business climate in Arkansas,” said Randy Zook, the president and CEO of the chamber and Associated Industries of Arkansas. But Scott Powell, an Alabama lawyer who represented the Arkansas farmers in the case, said the decision marked a victory not only for his clients, but for people and businesses in Arkansas “It helps them in deterring bad conduct,” said Powell. Bayer said it is studying the court’s opinion and considering its options.
     
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    Catch the Fever- It’ll Help You Fight Off Infection, Evidence Shows
     
    New research demonstrates that elevated body temperature plays a vital role on the generation of effective T-cell mediated immune response. –ScienceDaily (Nov. 1, 2011) — With cold and flu season almost here, the next time you’re sick, you may want to think twice before taking something for your fever. That’s because scientists have found more evidence that elevated body temperature helps certain types of immune cells to work better. This research is reported in the November 2011 issue of the Journal of Leukocyte Biology.—“An increase in body temperature has been known since ancient times to be associated with infection and inflammation,” said Elizabeth A. Repasky, Ph.D., a researcher involved in the work from the Department of Immunology at the Roswell Park Cancer Institute in Buffalo, New York. “Since a febrile response is highly conserved in nature (even so-called cold blooded animals move to warmer places when they become ill) it would seem important that we immunologists devote more attention to this interesting response.”—Scientists found that the generation and differentiation of a particular kind of lymphocyte, known as a “CD8+ cytotoxic T-cell” (capable of destroying virus-infected cells and tumor cells) is enhanced by mild fever-range hyperthermia. Specifically, their research suggests that elevated body temperature changes the T-cells’ membranes which may help mediate the effects of micro-environmental temperature on cell function. To test this, researchers injected two groups of mice with an antigen, and examined the activation of T-cells following the interaction with antigen presenting cells. Body temperature in half of the mice was raised by 2 degrees centigrade, while the other half maintained a normal core body temperature. In the warmed mice, results showed a greater number of the type of CD8 T-cells capable of destroying infected cells.—“Having a fever might be uncomfortable,” said John Wherry, Ph.D., Deputy Editor of the Journal of Leukocyte Biology, “but this research report and several others are showing that having a fever is part of an effective [U1]immune response. We had previously thought that the microbes that infect us simply can’t replicate as well when we have fevers, but this new work also suggests that the immune system might be temporarily enhanced functionally when our temperatures rise with fever. Although very high body temperatures are dangerous and should be controlled, this study shows that we may need to reconsider how and when we treat most mild fevers.”—-Story Source: The above story is reprinted from materials provided by Federation of American Societies for Experimental Biology, via EurekAlert!, a service of AAAS. –Journal Reference–T. A. Mace, L. Zhong, C. Kilpatrick, E. Zynda, C.-T. Lee, M. Capitano, H. Minderman, E. A. Repasky. Differentiation of CD8+ T cells into effector cells is enhanced by physiological range hyperthermia. Journal of Leukocyte Biology, 2011; 90 (5): 951 DOI: 10.1189/jlb.0511229
     
    Recipe—if a fever was ongoing to long or was getting to heated then the quickest way to reduce the heat would be vinegar as one method—you would take equal parts of water and vinegar 1:1 and then apply a wash cloth to the vinegar/ water solution this will immediately disperse the heat from the body –take the cloth of the person twirl it in the air then reapply –repeat this 3 times then re wet the washcloth and apply again or to another part of the body
    Should see the impact relatively quick
     
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    [U1]This is Something that alternative healers have been saying for Centuries!!!!!