EK
Antioxidant-rich watercress shows sports nutrition potential
Eight weeks of supplementation with watercress may reduce markers of oxidative stress and damage after
exhaustive exercise, suggests a new study—Healthy men consuming the green leafy vegetable had
less damage to DNA and lower levels of markers of oxidative stress, a result attributed to
the high antioxidant of watercress, report researchers from Edinburgh Napier University in Scotland
and the University of Ulster in Northern Ireland The lipid-soluble antioxidants alpha-tocopherol,
gamma-tocopherol and xanthophyll were all elevated following supplementation with
watercress, and, in doing so, indicates the potential for watercress to act as a source of blood-rich
antioxidants,” wrote the researchers in the British Journal of Nutrition”The increased concentration
of xanthophyll following the acute dose of watercress may therefore have played a
contributory role in the increased protection of lymphocyte DNA in this supplemented
group.” Exercise and oxidative stress Oxygen-breathing organisms naturally produce reactive oxygen
species (ROS), which play an important role in a range of functions, including cell signaling. However,
over production of these ROS from smoking, pollution, sunlight, high intensity exercise,
or simply aging, may overwhelm the body’s antioxidant defenses and lead to oxidative
stress. “As it has been shown that an over consumption of oral antioxidants may lead
to a pro-oxidant state, causing a disturbance in redox biochemistry, it is therefore
imperative that food sources naturally high in antioxidant vitamins are considered,
due to their capacity to provide increased systemic and cellular protection without
excessively elevating in vivo antioxidant vitamin concentrations,” explained the researchers.
In order to test the efficacy of watercress with respect to exhaustive exercise, the researchers recruited
10 healthy men with an average age of 23 to participate in their eight week study. Participants were
given 85 grams of watercress to consume every day for eight weeks. They also participated
in an eight week study with no watercress consumption to act as controls. Results from the exercise
tests showed that exercise during the no-watercress period led to an increase in DNA damage,
as well as increases in lipid peroxidation, a marker of oxidative stress. However, such increases
were not observed during the watercress period, said the researchers. Additionally, blood samples
revealed increased levels of fat-soluble antioxidants alpha-tocopherol, gamma-tocopherol
and xanthophylls. Antioxidant effects “In the present investigation, serum [levels of the pro-oxidant
compound hydrogen peroxide] H2O2 decreased following exhaustive exercise under both supplemented
conditions but increased in the control groups,” wrote the researchers, led by the University of
Ulster’s Gareth Davison. “These data would lend support to the suggestion that watercress may provide
effective in vivo protection against H2O2 production as a function of exercise. It is also plausible
that the elevated lipid-soluble antioxidants (under both supplemented protocols) are directly scavenging
superoxide and therefore result in a net decrease in H2O2 production. “The observed increase in
lipid-soluble antioxidants, as that demonstrated following exercise, may also play a
key role in the protection against cell membrane lipid peroxidation.” “The study demonstrates
that exhaustive aerobic exercise may cause DNA damage and lipid peroxidation; however,
these perturbations are attenuated by either short- or long-term watercress supplementation,
possibility due to the higher concentration of lipid-soluble antioxidants following
watercress ingestion.” —Source-http://dx.doi.org/10.1017/S0007114512000992 British Journal
of Nutrition Published online ahead of print, FirstView Articles, doi–10.1017/S0007114512000992
“Acute and chronic watercress supplementation attenuates exercise-induced peripheral mononuclear
cell DNA damage and lipid peroxidation” Authors: M.C. Fogarty, C.M. Hughes, G. Burke, J.C. Brown,
G.W. Davison
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The ability of an ethanol extract of Cinnamomum cassia to inhibit inflammatory action.– Src and spleen tyrosine kinase J
Ethnopharmacol. 2012 Jan 31;139(2):566-73—Authors: Yu T, Lee S, Yang WS, Jang HJ, Lee YJ, Kim TW, Kim SY, Lee J, Cho JY
Abstract
ETHNOPHARMACOLOGICAL RELEVANCE: Cinnamomum cassia Blume (Aceraceae) has been traditionally used to treat various inflammatory diseases such as gastritis. However, the anti-inflammatory mechanism of Cinnamomum cassia has not been fully elucidated. This study examined the anti-inflammatory mechanism of 95% ethanol extract (Cc-EE) of Cinnamomum cassia.–MATERIALS AND METHODS: The effect of Cc-EE on the production of inflammatory mediators in RAW264.7 cells and peritoneal macrophages was investigated. Molecular mechanisms underlying the effects, especially inhibitory effects, was elucidated by analyzing the activation of transcription factors and their upstream signaling, and by evaluating the kinase activity of target enzymes.–RESULTS: Cc-EE of Cinnamomum cassia diminished the production of nitric oxide (NO), tumor necrosis factor (TNF)-α, and prostaglandin (PG)E(2), in lipopolysaccharide (LPS)-activated RAW264.7 cells and peritoneal macrophages in a dose-dependent manner. Cc-EE also blocked mRNA expression of inducible NO synthase (iNOS), cyclooxygenase (COX)-2, and TNF-α by suppressing the activation of nuclear factor (NF)-κB, and simultaneously inhibited its upstream inflammatory signaling cascades, including spleen tyrosine kinase (Syk) and Src. Consistent with these findings,.—CONCLUSION: Cc-EE exerts strong anti- the extract directly blocked the kinase activities of Src and Syk inflammatory activity by suppressing Src/Syk-mediated NF-κB activation, which contributes to its major ethno-pharmacological role as an anti-gastritis remedy. Future work will be focused on determining whether the extract can be further developed as an anti-inflammatory drug.–PMID: 22155395 [PubMed – indexed for MEDLINE]
Recipe for Cinnamon bark—take Cinnamon Bark and add vodka to it in a blender and blend this at high speed—for 10 minutes + then stop blender –strain and use-1/4 tsp as needed
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Plant Diversity Is Key to Maintaining Productive Vegetation
NSF Cedar Creek LTER site experiments show what makes prairies and forests most productive. –ScienceDaily (May 3, 2012) — Vegetation, such as a patch of prairie or a forest stand, is more productive in the long run when more plant species are present, results of a new study show. The long-term study of plant biodiversity found that each species plays a role in maintaining a productive ecosystem, especially when a long time horizon is considered. The research found that every additional species in a plot contributed to a gradual increase in both soil fertility and biomass production over a 14-year period. This week’s issue of the journal Science published the results. They highlight the importance of managing for diversity in prairies, forests and crops, according to Peter Reich, lead author of the paper and a forest ecologist at the University of Minnesota. Reich and colleagues looked at how the effect of diversity on productivity of plants changed over the long-term.—Two large field experiments were conducted at the National Science Foundation’s (NSF) Cedar Creek Long-Term Ecological Research (LTER) site in Minnesota, one of 26 such NSF LTER sites around the globe in ecosystems from forests to grasslands, tundra to coral reefs.—“This study reveals what short-term experiments have missed: that the effects of biodiversity loss on ecosystems are more complex, severe and unpredictable than previously thought,” says Matt Kane, an NSF LTER program director.-“The work shows the importance of doing long-term research,” says Kane, “in this case documenting for the first time the critical importance of biodiversity for ecosystem health and sustainability.”–The biodiversity experiments at Cedar Creek are the longest-running such experiments in the world, says Reich. They contain plots with one, four, nine or 16 different species of plants.—The research used long-lived prairie plants, but serves as a model system for all vegetation, whether prairie, forest or row crop.-The study also showed how diversity works by demonstrating that different species have different ways of acquiring water, nutrients and carbon–and maintaining them in an ecosystem.–“Prior shorter-term studies, most about two years long, found that diversity increased productivity, but that having more than six or eight species in a plot gave no additional benefit,” Reich says. —–The scientists found that over a 14-year time span, all 16 species in the most diverse plots contributed more and more each year to higher soil fertility and biomass production.-“The take-home message,” says Reich, “is that when we reduce diversity in the landscape–think of a cornfield or a pine plantation or a suburban lawn–we are failing to capitalize on the valuable natural services that biodiversity provides.”-Co-authors of the paper are David Tilman, Forest Isbell, Kevin Mueller, Sarah Hobbie and Nico Eisenhauer of the University of Minnesota, and Dan Flynn of the University of Zurich.–Story Source—The above story is reprinted from materials provided by National Science Foundation. —Journal Reference-P. B. Reich, D. Tilman, F. Isbell, K. Mueller, S. E. Hobbie, D. F. B. Flynn, N. Eisenhauer. Impacts of Biodiversity Loss Escalate Through Time as Redundancy Fades. Science, 2012; 336 (6081): 589 DOI: 10.1126/science.1217909
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[U1]proteinuria from protein and urine) means the presence of an excess of serum proteins in the urine
[U2]In medicine, hematuria, or haematuria, is the presence of red blood cells (erythrocytes) in the urine. It may be idiopathic and/or benign, or it can be a sign that there is a kidney stone or a tumor in the urinary tract (kidneys, ureters, urinary bladder, prostate, and urethra), ranging from trivial to lethal
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Show of the Week May 21-2012
Community-Acquired MRSA Is Spreading
Blue Light Destroys Antibiotic-Resistant Staph Infection
Clustering MRSA in Europe Indicates Diffusion Through Regional Health-Care Networks
Overcrowding And Understaffing In Hospitals Increases Levels Of MRSA Infections
Cross-Reactivity Between Peanuts and Other Legumes Can Lead to Serious Allergic Reactions
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Community-Acquired MRSA Is Spreading
ScienceDaily (Mar. 31, 2008) — Drug resistant hospital superbugs like MRSA have been kept under control in Denmark for more than 30 years. But the latest reports say that in the last 10 years MRSA cases have risen 10 times as new strains of bacteria with resistance genes spread through the community, scientists heard April 1 2008 at the Society for General Microbiology’s 162nd meeting.—“The new threat is MRSA transmission in the community, without infected people visiting a hospital or care home themselves, where they might be expected to risk contact with drug resistant bacteria”, says Professor Robert Skov from the Statens Serum Institut in Copenhagen, Denmark.—-“The spread of community acquired MRSA among the general population creates a huge problem for us”, says Professor Skov. “Some infected people will inevitably be hospitalised themselves, or visit friends and relatives who are patients in hospitals. Or they could be health care workers and so will increase the risk of outbreaks of these new types of MRSA. These community strains have evolved independently of the hospital strains and so present a whole new series of problems for control and treatment”.—Staphylococcus aureus is common and usually harmless, it is carried by 25-40% of the population on their skin and in their noses. But if it gets inside the body through an injury, cut, surgical operation or through a catheter it can cause infections. These infections are often mild, causing boils or pimples, but in some cases they may develop into more serious infections affecting the bloodstream, joints and bones.—These serious infections were first brought under control with the discovery of penicillin, but as resistance to antibiotics has spread, new and dangerous superbug strains such as MRSA have emerged. These are far more difficult to treat and can cause life-threatening infections, especially in patients with impaired immune systems or low white blood cell counts.–[U1]”We have managed to hold the frequency of MRSA cases down to under one per cent in Denmark for over 30 years. But in 1997 we recognised the first cases of community acquired MRSA, a new strain independent of hospital and nursing home contacts, in a young adult and two families in a rural town”, says Professor Skov. “From the families we traced the superbug being transmitted through a kindergarten, a school, a factory and a farm. Between 1999 and 2006 the number of community acquired MRSA infections increased from 11 to 175 a year, making up more than 22% of all MRSA infections, as a rising proportion.”—The Danish scientists found that the most common method of superbug transmission was from one family member to another, with children and younger adults most affected. And many of the infected families had relations in other countries with a high incidence of MRSA in the population.[U2]–The Danish health system responded by introducing new national guidelines in November 2006 designed to prevent MRSA spreading, including increased barrier precautions and isolation nursing in both hospitals and nursing homes. The guidelines appear to be successful, as a small decrease in cases has been observed. The results of these experiences, which have helped to stop the rising epidemic of MRSA, will be published in health journals shortly.—Story Source–The above story is reprinted from materials provided by Society for General Microbiology,
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Blue Light Destroys Antibiotic-Resistant Staph Infection
ScienceDaily (Jan. 29, 2009) — Two common strains of methicillin-resistant Staphylococcus aureus, commonly known as MRSA, were virtually eradicated in the laboratory by exposing them to a wavelength of blue light, in a process called photo-irradiation.—Antibiotic-resistant bacterial infections represent an important and increasing public health threat. At present, fewer than 5% of staphylococcal strains are susceptible to penicillin, while approximately 40%-50% of Staph aureus isolated have developed resistance to newer semisynthetic antibiotics such as methicillin as well.—-Chukuka S. Enwemeka, Deborah Williams, Sombiri K. Enwemeka, Steve Hollosi, and David Yens from the New York Institute of Technology (Old Westbury, NY) had previously demonstrated that photo-irradiation using 405-nm light destroys MRSA strains grown in culture. In the current study, “Blue 470-nm Light Kills Methicillin-Resistant Staphylococcus aureus (MRSA) in Vitro,” the authors exposed bacterial colonies of MRSA to various doses of 470-nm light, which emits no UV radiation.—–The two MRSA populations studied—the US-300 strain of CA-MRSA and the IS-853 strain of HA-MRSA—represent prominent community-acquired and hospital-acquired strains, respectively.—The authors report that the higher the dose of 470-nm blue light, the more bacteria were killed. High-dose photo-irradiation was able to destroy 90.4% of the US-300 colonies and the IS-853 colonies. The effectiveness of blue light in vitro suggests that it should also be effective in human cases of MRSA infection, and particularly in cutaneous and subcutaneous infections.—“It is inspiring that an inexpensive naturally visible wavelength of light can eradicate two common strains of MRSA. Developing strategies that are capable of destroying MRSA, using mechanisms that would not lead to further antibiotic resistance, is timely and important for us and our patients,” says Chukuka S. Enwemeka, PhD, FACSM, Co-Editor-in-Chief of the Journal and first author of the study.—The article will appear in the April 2009 issue (Volume 27, Number 2) of the peer-reviewed journal Photomedicine and Laser Surgery. —-Story Source-The above story is reprinted from materials provided by Mary Ann Liebert, Inc./Genetic Engineering News.
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Clustering MRSA in Europe Indicates Diffusion Through Regional Health-Care Networks
ScienceDaily (Jan. 11, 2010) — A new study finds that methicillin-resistant Staphylococcus aureus (MRSA) -responsible for several difficult-to-treat infections including blood poisoning and pneumonia and a particular problem in hospitals — occurs in distinct geographical clusters across Europe, indicating that MRSA is being diffused by patients moving between hospitals rather than spreading freely in the community.—The study, published in PLoS Medicine, used an interactive Web tool to map different strains of the Staphylococcus aureus (S. aureus) bacterium across the continent.—-MRSA infections have become more prevalent in hospitals over the past ten years, and information about its geographical distribution could help us to understand how it spreads and how to control it.—In 2006 Hajo Grundmann, of the University Medical Centre in Groningen in the Netherlands, and colleagues assembled a large group of collaborators in 450 European hospitals located in 26 different countries. These hospitals collected both MRSA and methicillin-sensitive S. aureus (MSSA) isolates from infected patients — MRSA emerges when MSSA clones acquire resistance to antibiotics. National laboratories identified specific strains of S. aureus by molecular typing and entered this information into a Web-based mapping application which is publicly available (http://www.spatialepidemiology.net/srl-maps).—The results show that strains of MRSA tend to cluster within regional borders and, in several instances, were associated with individual hospitals. This suggests that MRSA is mainly spread by patients who are repeatedly admitted to different hospitals. “Control efforts aimed at interrupting the spread within and between health care institutions may not only be feasible but ultimately successful,” conclude the researchers.—Franklin Lowy of Columbia University — uninvolved in the research — discusses the study in a Perspective and suggests that it “illustrates the ability of spatial mapping techniques to help understand the spread of new or re-emerging pathogens at the local as well as the international level”—Story Source–The above story is reprinted from materials provided by Public Library of Science, via EurekAlert!, a service of AAAS. —Journal References–Grundmann H, Aanensen DM, van den Wijngaard CC, Spratt BG, Harmsen D, et al. Geographic Distribution of Staphylococcus aureus Causing Invasive Infections in Europe: A Molecular-Epidemiological Analysis. PLoS Medicine, 2010; 7 (1): e1000215 DOI: 10.1371/journal.pmed.1000215—Lowy FD. Mapping the Distribution of Invasive Staphylococcus aureus across Europe. PLoS Medicine, 2010; 7 (1): e1000205 DOI: 10.1371/journal.pmed.1000205
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Overcrowding And Understaffing In Hospitals Increases Levels Of MRSA Infections
A new study found that overcrowding and understaffing caused higher levels of MRSA because of its impact on hand hygiene, the number of contacts between healthcare workers and different patients, overburdening of screening and isolation programmes and by causing staff burnout.
ScienceDaily (June 24, 2008) — A review article authored by a University of Queensland academic has found overcrowding and understaffing in hospitals are two key factors in the transmission of MRSA (Meticillin — Resistant Staphylococcus Aureus) infections worldwide.—Dr Archie Clements, from the School of Population Health, reported overcrowding and understaffing increased levels of MRSA infections, which lead to increased inpatient hospital stay, bed blocking, overcrowding and more MRSA infections.—The review included information from 140 papers and Dr Clements was part of a team of seven authors.–The article titled: Overcrowding and understaffing in modern health-care systems: key determinants in Meticillin-Resistant Staphylococcus Aureus (MRSA) transmission, was published today in the July edition of The Lancet Infectious Diseases.—Dr Clements said MRSA was an antibiotic-resistant type of Staphylococcus Aureus, a common bacteria present on the skin and in the nostrils of many healthy people.–“MRSA often colonises hospital patients to no ill effect but, if present in a surgical wound or carried to the bloodstream by an intravenous catheter, it can cause serious infection and possibly the death of the patient,” he said.—Dr Clements said overcrowding and understaffing caused higher levels of MRSA because of its impact on hand hygiene, the number of contacts between healthcare workers and different patients, overburdening of screening and isolation programmes and by causing staff burnout.—“MRSA worsens overcrowding because patients with MRSA stay longer in hospitals and, if isolation in multi-bed rooms is done, beds not occupied by the MRSA patient are also closed to other patients,” he said.–“Overcrowding and understaffing, root causes of the MRSA problem, are partly related to policy that promotes high patient throughput and fewer beds, and partly to a diminishing, ageing health care workforce.—“These problems are likely to continue or worsen, and impact on patient health and safety, unless new ways are found to reduce overcrowding and understaffing of hospitals.”—Dr Clements hoped to use the findings to initiate more research into the relationship between overcrowding/understaffing and MRSA to answer questions such as: “What are the optimal bed occupancy and staffing rates for preventing avoidable MRSA infections while maintaining current levels of care?” and “What is the likely impact of MRSA interventions under conditions of overcrowding and understaffing?”—Story Source-The above story is reprinted from materials provided by University of Queensland.
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Cross-Reactivity Between Peanuts and Other Legumes Can Lead to Serious Allergic Reactions
ScienceDaily (May 15, 2012) — Food allergies pose a serious and growing problem in the West. Many foods can lead to allergic reactions and this situation is further complicated by so-called cross-reactions, whereby an allergy to one particular food can trigger allergic reactions to another food. There are no treatments available for food allergies[U3], but the establishment of two mouse models can be used to develop and test new forms of treatment, for example vaccines.[U4]—Around 4-8% of children and 1-4% of adults in the West suffer from food allergy. The most common causes of food allergy are peanuts, nuts, soya, milk, fish, shellfish, flour and eggs, but a total of over 170 different foods have been found to result in allergic reactions. In addition, there are the allergies that arise as a result of cross reactions to other types of food. The only form of treatment is to avoid all consumption of the food that the person is allergic to. Allergenic substances that are hidden in processed foods therefore pose a particular problem for people allergic to foods.—-Nina E. Vinje’s doctoral research has led to the establishment of two mouse models for food allergy to the legumes lupin and Fenugreek (Trigonella foenum-graecum). These models have been used to test whether legumes such as soya, peanuts, Fenugreek and lupin can trigger allergic reactions in mice that are already allergic to lupin and Fenugreek respectively. It is important to establish good animal models for food allergies because the development of an allergic immune response depends on a complicated interaction between types of cells in several different organs. Vinje has made every effort to reduce the use of laboratory animals to a minimum during her project. For this reason, she used an advanced statistical method to develop the models in order to gain as much information as possible from the use of as few animals as possible.—Lupin and Fenugreek are examples of so-called “new” and “hidden” allergens which have been introduced to Norway, for instance in ready-made meals, over the last 10-15 years. Lupin was introduced as a supplement to wheat flour in various bakery products because of its ability to promote good baking. Fenugreek is used as an ingredient in foods such as curry, chutney and spiced tea and is well known in Asian dishes. Packaging often does not show whether Fenugreek is an ingredient, as the consumer information merely says “spices.” Both lupin and Fenugreek can lead to serious cross-reactions in patients with peanut allergy, in contrast to other legumes such as soya and peas. This fact was discovered due to messages sent in to the Food Allergy Register (www.fhi.no/matallergireg) and these discoveries contributed to the EU making it obligatory to mark lupin as an ingredient in foods.—The established mice models can be used to try out new treatments, for example vaccines against food allergies[U5]. A vaccine must be tested on animals before it can be tested on humans, both in order to find out whether it works and to make sure that it does not cause serious side effects. New foods that are to be released onto the market will also be able to be tested to see if they can cause allergies. Mice can be used for this purpose because their immune system is well charted and is relatively similar to that of humans. This means that researchers can study the clinical, anaphylactic (shock) reactions associated with food allergy in mice in order to gain a greater understanding of the mechanisms that cause allergic reactions in humans.—Vinje’s doctoral project was carried out at the Norwegian Institute of Public Health and researchers and fellows at the Norwegian Veterinary Institute and the Norwegian School of Veterinary Science have been major collaborators.–Story Source-The above story is reprinted from materials provided by Norwegian School of Veterinary Science, via AlphaGalileo.
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[U1]This is easily achieved today with the chemtrail dropping exhausting our immune system and allow for the low white blood cell counts to take place allowing a inept pathogen to become excessively dangerious—as a result of this Genetic engineering of dis eases-we will see a considerably amount of infection taking place with the youth and elderly primarily—which will either be precriibed with drugs that will be ineffective or the elderly eill be euphanized with a vaccine
[U2]So it is not genetic but rather a concentrated infecting of family or groups or communities which would mean a specific group of people would be infected and whole bloodlines could be wiped
[U3]Amazing—when you read this —this would basically tell you the way people are consuming there foods and the combinations —are the issue—when we combine the GMO which compromises DNA and genes in the human body and then further combine the different foods tat are genetically modified we are getting a response to the debilitating of the immune system and digestive system not to mention the other system impacted or exasperated to remove these
[U4]Notice how quick to mention a vaccine rather then a technique or life style to change!!!??
[U5]Never Changes –instead of a change to a higher quality of food in the supermarket and apply a little self discipline—You may be surprised to the increase in health
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Show of the Week May 25-2012
Smart meters pose health hazard
A Moderate acute increase in physical activity enhances nutritive flow and the muscle protein
anabolic response
Fructose The Saboteur of Brain
Eating High Levels Of Fructose Impairs Memory In Rats
Butter differs from olive oil and sunflower oil in its effects on postprandial lipemia and triacylglycerol
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Smart meters pose health hazard
Montreal Gazette Montreal Gazette –
Hydro-Québec’s proposed rollout of 3.8 million wireless smart meters “may constitute a risk of serious, as well as irreversible, damage to health,” according to a report by a U.S. public health professional testifying before Quebec’s energy board Thursday.—David Carpenter, director of the University at Albany’s Institute for Health and the Environment, urged that precautionary measures be taken to offset potential health problems related to radiofrequency emissions from the wireless meters.—There hasn’t yet been a comprehensive study on the impact of the relatively new devices and their RF radiation on human health, Carpenter told the board.—While the body of evidence is incomplete, it “is strong enough that as a public health official it is my responsibility to tell you that we should do what we can to reduce exposure in ways that are neither excessively expensive or excessively regulatory,” he said.—-“If government does not acknowledge that there is reason for caution, it will be like the situation we had with smoking and lung cancer.”–The meters that Hydro-Québec proposes to use in its $1-billion project to deploy smart meters across the province by 2017 would be mostly located on exterior walls.—But meters situated inside occupied rooms such as kitchens would increase exposure to RF energy that would be especially problematic for children, according to Carpenter’s report and testimony Thursday.—In a report filed with the Régie de l’énergie, Carpenter said that alternatives include hardwired technology.-Meters inside homes should be moved to the outside or at least positioned so that they don’t face occupants.–Carpenter was retained by the Association québécoise de lutte contre la pollution atmosphérique and Stratégies Énergétiques, both intervenors in the case. Carpenter was not accorded the status of an expert witness by board president Richard Lassonde on Thursday.–Lassonde accepted Hydro-Québec’s key position that Carpenter had not himself done research directly related to RF radiation.–Carpenter, whose curriculum vitae runs to 32 pages, is the former director of the third-largest public health lab in the U.S., testified about RF and power-line emissions and cancer before the U.S. President’s Cancer Panel in 2009 and is among the external reviewers of grant proposals for Quebec’s cancer program.The hearings continue.
[email protected]
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A moderate acute increase in physical activity enhances nutritive flow and the muscle protein anabolic response to mixed nutrient intake in older adults
Kyle L Timmerman, Shaheen Dhanani, Erin L Glynn, Christopher S Fry, Micah J Drummond, Kristofer Jennings, Blake B Rasmussen, and Elena Volpi
+ Author Affiliations
1From the Departments of Nutrition & Metabolism (KLT, MJD, and BBR), Internal Medicine (EV), and Preventive Medicine and Community Health (KJ); Sealy Center on Aging (KLT, SD, MJD, BBR, and EV); Division of Rehabilitation Sciences (KLT, ELG, CSF, MJD, and BBR); and the Institute for Translational Sciences (KLT, MJD, BBR, and EV), University of Texas Medical Branch, Galveston, TX.
+ Author Notes
↵2 Supported by NIH R01 AG018311, P30 AG024832, S10 RR16650, T32 HD07539, and UL1 RR029876. Definity was provided by Lantheus Medical Imaging, North Billerica, MA, under Definity Research grant no. 26020.
↵3 Address correspondence to E Volpi, 301 University Boulevard, Galveston, TX 77555-0460. E-mail: [email protected]
Abstract
Background: Nutrient stimulation of muscle protein anabolism is blunted with aging and may contribute to the development and progression of sarcopenia in older adults. This is likely due to insulin resistance of protein metabolism and/or endothelial dysfunction with a reduction in nutritive flow, both of which can be improved by aerobic exercise. –Objective: Our objective was to determine whether increasing physical activity can enhance the muscle protein anabolic effect of essential amino acid (EAA) + sucrose intake in older subjects by improving nutritive flow and/or insulin signaling. –Design: Using a randomized crossover design, we measured in older subjects [n = 6, 70 ± 3 y of age, BMI (in kg/m2) of 25 ± 1] the acute effects of increasing physical activity with aerobic exercise, as compared with normal sedentary lifestyle, on the response of blood flow, microvascular perfusion, insulin signaling, and muscle protein kinetics to EAA+sucrose intake. –Results: No differences between treatment groups were found in the basal state[U1]. The change from the basal state in blood flow, muscle perfusion, phenylalanine delivery, net balance, and muscle protein synthesis during the consumption of EAA+sucrose was significantly higher after the exercise than after the control treatment (P < 0.05). Insulin signaling increased during EAA+sucrose ingestion in both groups (P < 0.05). –Conclusions: Our data indicate that a prior bout of aerobic exercise increases the anabolic effect of nutrient intake in older adults. This effect appears to be mediated by an exercise-induced improvement in nutrient-stimulated vasodilation and nutrient delivery to muscle rather than to improved insulin signaling. This trial was registered at clinicaltrials.gov as NCT00690534.
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Fructose The Saboteur of Brain
This Is Your Brain On Sugar– Study in Rats Shows High-Fructose Diet Sabotages Learning, Memory—New research suggests that binging on soda and sweets for as little as six weeks may make you stupid. —ScienceDaily (May 15, 2012) — Attention, college students cramming between midterms and finals: Binging on soda and sweets for as little as six weeks may make you stupid.——A new UCLA rat study is the first to show how a diet steadily high in fructose slows the brain, hampering memory and learning — and how omega-3 fatty acids can counteract the disruption. The peer-reviewed Journal of Physiology publishes the findings in its May 15 edition.—“Our findings illustrate that what you eat affects how you think,” said Fernando Gomez-Pinilla, a professor of neurosurgery at the David Geffen School of Medicine at UCLA and a professor of integrative biology and physiology in the UCLA College of Letters and Science. “Eating a high-fructose diet over the long term alters your brain’s ability to learn and remember information. But adding omega-3 fatty acids to your meals can help minimize the damage.[U2]”–While earlier research has revealed how fructose harms the body through its role in diabetes, obesity and fatty liver, this study is the first to uncover how the sweetener influences the brain.—The UCLA team zeroed in on high-fructose corn syrup, an inexpensive liquid six times sweeter than cane sugar, that is commonly added to processed foods, including soft drinks, condiments, applesauce and baby food. The average American consumes more than 40 pounds of high-fructose corn syrup per year, according to the U.S. Department of Agriculture. “We’re not talking about naturally occurring fructose in fruits, which also contain important antioxidants,” explained Gomez-Pinilla, who is also a member of UCLA’s Brain Research Institute and Brain Injury Research Center. “We’re concerned about high-fructose corn syrup that is added to manufactured food products as a sweetener and preservative.”—Gomez-Pinilla and study co-author Rahul Agrawal, a UCLA visiting postdoctoral fellow from India, studied two groups of rats that each consumed a fructose solution as drinking water for six weeks. The second group also received omega-3 fatty acids in the form of flaxseed oil and docosahexaenoic acid (DHA[U3]), which protects against damage to the synapses — the chemical connections between brain cells that enable memory and learning.[U4]—“DHA is essential for synaptic function — brain cells’ ability to transmit signals to one another,” Gomez-Pinilla said. “This is the mechanism that makes learning and memory possible. Our bodies can’t produce enough DHA, so it must be supplemented through our diet.”–The animals were fed standard rat chow and trained on a maze twice daily for five days before starting the experimental diet. The UCLA team tested how well the rats were able to navigate the maze, which contained numerous holes but only one exit. The scientists placed visual landmarks in the maze to help the rats learn and remember the way. — Six weeks later, the researchers tested the rats’ ability to recall the route and escape the maze. What they saw surprised them.—-“The second group of rats navigated the maze much faster than the rats that did not receive omega-3 fatty acids,” Gomez-Pinilla said. “The DHA-deprived animals were slower, and their brains showed a decline in synaptic activity. Their brain cells had trouble signaling each other, disrupting the rats’ ability to think clearly and recall the route they’d learned six weeks earlier.”—The DHA-deprived rats also developed signs of resistance to insulin, a hormone that controls blood sugar and regulates synaptic function in the brain. A closer look at the rats’ brain tissue suggested that insulin had lost much of its power to influence the brain cells.—“Because insulin can penetrate the blood-brain barrier, the hormone may signal neurons to trigger reactions that disrupt learning and cause memory loss,” Gomez-Pinilla said.—He suspects that fructose is the culprit behind the DHA-deficient rats’ brain dysfunction. Eating too much fructose could block insulin’s ability to regulate how cells use and store sugar for the energy required for processing thoughts and emotions.—“Insulin is important in the body for controlling blood sugar, but it may play a different role in the brain, where insulin appears to disturb memory and learning,” he said. “Our study shows that a high-fructose diet harms the brain as well as the body. This is something new.”–Gomez-Pinilla, a native of Chile and an exercise enthusiast who practices what he preaches, advises people to keep fructose intake to a minimum and swap sugary desserts for fresh berries and Greek yogurt, which he keeps within arm’s reach in a small refrigerator in his office. An occasional bar of dark chocolate that hasn’t been processed with a lot of extra sweetener is fine too, he said.—Still planning to throw caution to the wind and indulge in a hot-fudge sundae? Then also eat foods rich in omega-3 fatty acids, like salmon, walnuts and flaxseeds, or take a daily DHA capsule. Gomez-Pinilla recommends one gram of DHA per day.–“Our findings suggest that consuming DHA regularly protects the brain against fructose’s harmful effects,” said Gomez-Pinilla. “It’s like saving money in the bank. You want to build a reserve for your brain to tap when it requires extra fuel to fight off future diseases.”—The UCLA study was funded by the National Institute of Neurological Disorders and Stroke. Gomez-Pinilla’s lab will next examine the role of diet in recovery from brain trauma.-Story Source–The above story is reprinted from materials provided by University of California, Los Angeles (UCLA), Health Sciences, via Newswise. —Journal Reference—R. Agrawal, F. Gomez-Pinilla. ‘Metabolic syndrome’ in the brain: deficiency in omega-3 fatty acid exacerbates dysfunctions in insulin receptor signalling and cognition. The Journal of Physiology, 2012; 590 (10): 2485 DOI: 10.1113/jphysiol.2012.230078
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Eating High Levels Of Fructose Impairs Memory In Rats
Diets high in fructose — a type of sugar found in most processed foods and beverages — impaired the spatial memory of adult rats—ScienceDaily (July 16, 2009) — Researchers at Georgia State University have found that diets high in fructose — a type of sugar found in most processed foods and beverages — impaired the spatial memory of adult rats.—Amy Ross, a graduate student in the lab of Marise Parent, associate professor at Georgia State’s Neuroscience Institute and Department of Psychology, fed a group of Sprague-Dawley rats a diet where fructose represented 60 percent of calories ingested during the day.—She placed the rats in a pool of water to test their ability to learn to find a submerged platform, which allowed them to get out of the water. She then returned them to the pool two days later with no platform present to see if the rats could remember to swim to the platform’s location.-“What we discovered is that the fructose diet doesn’t affect their ability to learn,” Parent said. “But they can’t seem to remember as well where the platform was when you take it away. They swam more randomly than rats fed a control diet.”—Fructose, unlike another sugar, glucose, is processed almost solely by the liver, and produces an excessive amount of triglycerides [U5]— fat which get into the bloodstream. Triglycerides can interfere with insulin signaling in the brain, which plays a major role in brain cell survival and plasticity, or the ability for the brain to change based on new experiences.—Results were similar in adolescent rats, but it is unclear whether the effects of high fructose consumption are permanent, she said.—Parent’s lab works with Timothy Bartness, Regents’ Professor of Biology, and John Mielke of the University of Waterloo in Waterloo, Ontario, Canada to examine how diet influences brain function.—Although humans do not eat fructose in levels as high as rats in the experiments, the consumption of foods sweetened with fructose — which includes both common table sugar, fruit juice concentrates, as well as the much-maligned high fructose corn syrup — has been increasing steadily. High intake of fructose is associated with numerous health problems, including insulin insensitivity, type II diabetes, obesity and cardiovascular disease.—“The bottom line is that we were meant to have an apple a day as our source of fructose,” Parent said. “And now, we have fructose in almost everything.” Moderation is key, as well as exercise, she said.—Exercise is a next step in ongoing research, and Parent’s team will investigate whether exercise might mitigate the memory effects of high fructose intake. Her lab is also researching whether the intake of fish oil can prevent the increase of triglycerides and memory deficits. Results from that research will be presented by her graduate student Emily Bruggeman at the 2009 Society for Neuroscience meeting in Chicago this fall.–Story Source-The above story is reprinted from materials provided by Georgia State University.
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Butter differs from olive oil and sunflower oil in its effects on postprandial lipemia and triacylglycerol-rich lipoproteins after single mixed meals in healthy young men.
Mekki N, Charbonnier M, Borel P, Leonardi J, Juhel C, Portugal H, Lairon D.
Source—Unité 476-Institut National de la Santé et de la Recherche Médicale, Human Nutrition and Lipids, National Institute of Health and Medical Research, Université de la Méditerranée, 13009 Marseille, France.
Abstract—-Accumulation of postprandial triacylglycerol-rich lipoproteins is generated by assimilation of ingested dietary fat and has been increasingly related to atherogenic risk. Nevertheless, the influence of different kinds of dietary fatty acids on postprandial lipid metabolism is not well established, except for (n-3) polyunsaturated long-chain fatty acids. Our goal was to evaluate the effects of test meals containing a common edible fat source of saturated (butter), monounsaturated (olive oil) or (n-6) polyunsaturated (sunflower oil) fatty acids on postprandial lipid and triacylglycerol-rich lipoprotein responses. After a 12-h fast, 10 healthy young men ingested mixed meals containing 0 g (control) or 40 g fat, provided as butter, olive oil or sunflower oil in a random order.[U6] Fasting and postmeal blood samples were collected for 7 h. The no-fat test meal did not elicit any change over baseline except for plasma phospholipids, insulin and nonesterified fatty acids. Conversely, the three fat-containing meals elicited bell-shaped postprandial changes (P < 0.05) in serum triacylglycerols, free and esterified cholesterol, and nonesterified fatty acids. The butter meal induced a lower postprandial rise of triacylglycerols in serum and chylomicrons (incremental AUC, mmol.h/L: 0.72) than the two unsaturated oils (olive oil: 1.6, sunflower oil: 1.8), which did not differ. Circulating chylomicrons were smaller after the butter meal than after the two vegetable oil meals. The in vitro susceptibility of circulating chylomicrons to hydrolysis by postheparin plasma was higher after sunflower oil than after butter or olive oil. We conclude that butter results in lower postprandial lipemia and chylomicron accumulation in the circulation of young men than olive or sunflower oils after consumption of a single mixed meal.
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[U1]No difference in a state of rest—both the same –due to both are doing the same thing–Nothing
[U2]Minimizing damage??? Is this stupid as well—if you know this is causing brain impediment then the best cource is not to consume—the issue is the addictive nature of HFCS or Corn Sugar as it is called these days
[U3]Flax seed would be acceptable—algae source as well—Avoid the fish oils and utilize the 3’s with 6 and nine—never utilize them sepreately
[U4]You can as well utilize wheatgerm oil and Sunflower Lecithin
[U5]NOTICE HERE SUGAR Not Fat triggers Triglycerides—not cholesterol
[U6]The procedure they used to get there conclusions
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Show of the Week May 28-2012
Genetic Mutation in African Malaria Parasite Shown to Give Resistance to Best Drugs
Interactions Between Species: Powerful Driving Force Behind Evolution?
Antiviral activity of phytochemicals: a comprehensive review
Effects of a nutrient mixture on infectious properties
Nutrient mixture containing ascorbic acid, green tea extract and amino acids suppression of influenza A virus
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Genetic Mutation in African Malaria Parasite Shown to Give Resistance to Best Drugs
ScienceDaily (Apr. 27, 2012) — Scientists have identified genetic mutations[U1] in the deadliest malaria parasite in Africa that are giving it resistance to one of the most powerful anti-malarial drugs. The researchers say their findings are a further warning that the best weapons against malaria could become obsolete.–The artemisinin group of drugs are the most effective and widely used treatments for malaria. They are most powerful and less likely to be resisted by the malaria parasite when used with other drugs as artemisinin-based combination therapies (ACTs). But the new study confirms previous suggestions that mutations in a key part of the parasite can provide resistance to artemether, one of the two most effective artemisinins.—The research group, led by a team at St George’s, University of London, discovered artemether resistance in parasite samples taken from 11 of the 28 malaria-infected patients in the study. On average, artemether’s effectiveness was reduced by half. Each parasite was found to have the same genetic mutations.[U2]—The patients were infected by malaria parasite-carrying mosquitoes while travelling abroad, mostly in sub-Saharan Africa, home to 90 per cent of the one million people killed worldwide each year by malaria.—Study lead Professor Sanjeev Krishna said: “Artemether and ACTs are still very effective, but this study confirms our fears of how the parasite is mutating to develop resistance. Drug resistance could eventually become a devastating problem in Africa, and not just in south east Asia where most of the world is watching for resistance. Effective alternative treatments are currently unaffordable for most suffering from malaria[U3]. Finding new drugs is, therefore, crucial.” In the study, published online April 27, 2012 in BioMed Central’s open access journal Malaria Journal, the researchers tested samples from patients infected with the Plasmodium falciparum parasite. This parasite causes the deadliest form of malaria, and is responsible for nine out of 10 malaria deaths. [U4]The parasites were assessed for their sensitivity to four artemisinins — artemisinin itself, artemether, dihydroartemisinin and artesunate.—The 11 parasites showing artemether resistance had the same genetic mutations in an internal system called the calcium pump. This is used to transport calcium, crucial for the parasite to function. The researchers already suspected that the calcium pump — which they first showed was a target for artemisinins to work on in 2003 — had the potential to develop artemisinin resistance. But this had been difficult to confirm until now.—Artemether resistance was strongest in several cases where a separate mutation in another transport system — a protein called pfmdr1, already associated with drug resistance — also occurred.—The effectiveness of the other artemisinins was not significantly affected by the mutations. This may be because they were able to work on other transport systems in the parasite, compensating for the effects of resistance mutations in the calcium pump.—However, Professor Krishna added: “At the moment, we do not know if the other artemisinins will follow suit, but given the shared chemistry they have with artemether it is tempting to think that they would.”—He added that resistance could be a result of the increasing use of ACTs, 300 million doses of which were dispensed worldwide in 2011. Greater use could offer the parasites more opportunities to develop genetic mutations that provide resistance. This could, the researchers say, lead to a repeat of how the parasite developed resistance to pre-artemisinin drugs such as chloroquine. Incorrect use of anti-malarials, such as not completing the treatment course or taking sub-standard drugs, could aid this process.—Professor Krishna said: “New drug development is paramount, but it is vital that we also learn more about how artemisinins work so we can tailor ACT treatments to be effective for as long as possible.”—-Story Source-The above story is reprinted from materials provided by University of St George’s London, via AlphaGalileo. –Journal Reference-Dylan R Pillai, Rachel Lau, Krishna Khairnar, Rosalba Lepore, Allegra Via, Henry M Staines, Sanjeev Krishna. Artemether resistance in vitro is linked to mutations in PfATP6 that also interact with mutations in PfMDR1 in travellers returning with Plasmodium falciparum infections. Malaria Journal, 2012; 11 (1): 131 DOI: 10.1186/1475-2875-11-131
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Interactions Between Species: Powerful Driving Force Behind Evolution?
Computer rendering of virus particles. In a new study, researchers used fast-evolving viruses to observe hundreds of generations of evolution. They found that for every viral strategy of attack, the bacteria would adapt to defend itself, which triggered an endless cycle of co-evolutionary change. —ScienceDaily (Feb. 25, 2010) — Scientists at the University of Liverpool have provided the first experimental evidence that shows that evolution is driven most powerfully by interactions between species, rather than adaptation to the environment.—The team observed viruses as they evolved over hundreds of generations to infect bacteria. They found that when the bacteria could evolve defences, the viruses evolved at a quicker rate and generated greater diversity, compared to situations where the bacteria were unable to adapt to the viral infection.–The study shows, for the first time, that the American evolutionary biologist Leigh Van Valen was correct in his ‘Red Queen Hypothesis’. The theory, first put forward in the 1970s, was named after a passage in Lewis Carroll’s Through the Looking Glass in which the Red Queen tells Alice, ‘It takes all the running you can do to keep in the same place’. This suggested that species were in a constant race for survival and have to continue to evolve new ways of defending themselves throughout time.—Dr Steve Paterson, from the University’s School of Biosciences, explains: “Historically, it was assumed that most evolution was driven by a need to adapt to the environment or habitat. The Red Queen Hypothesis challenged this by pointing out that actually most natural selection will arise from co-evolutionary interactions with other species, not from interactions with the environment.—“This suggested that evolutionary change was created by ‘tit-for-tat’ adaptations by species in constant combat. This theory is widely accepted in the science community, but this is the first time we have been able to show evidence of it in an experiment with living things.”—Dr Michael Brockhurst said: “We used fast-evolving viruses so that we could observe hundreds of generations of evolution. We found that for every viral strategy of attack, the bacteria would adapt to defend itself, which triggered an endless cycle of co-evolutionary change. We compared this with evolution against a fixed target, by disabling the bacteria’s ability to adapt to the virus.–“These experiments showed us that co-evolutionary interactions between species result in more genetically diverse populations, compared to instances where the host was not able to adapt to the parasite. The virus was also able to evolve twice as quickly when the bacteria were allowed to evolve alongside it.”—The team used high-throughput DNA sequencing technology at the Centre for Genomic Research to sequence thousands of virus genomes. The next stage of the research is to understand how co-evolution differs when interacting species help, rather than harm, one another.—-The research is published in Nature and was supported by funding from the Natural Environment Research Council (NERC); the Wellcome Trust; the European Research Council and the Leverhulme Trust.—-Story Source-The above story is reprinted from materials provided by University of Liverpool, via EurekAlert!, a service of AAAS. –Journal Reference–Steve Paterson, Tom Vogwill, Angus Buckling, Rebecca Benmayor, Andrew J. Spiers, Nicholas R. Thomson, Mike Quail, Frances Smith, Danielle Walker, Ben Libberton, Andrew Fenton, Neil Hall & Michael A. Brockhurst. Antagonistic coevolution accelerates molecular evolution. Nature, 2010; DOI: 10.1038/nature08798
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Antiviral activity of phytochemicals: a comprehensive review.
Naithani R, Huma LC, Holland LE, Shukla D, McCormick DL, Mehta RG, Moriarty RM.
Source–Department of Chemistry, University of Illinois at Chicago, Chicago-60607, USA. rajesh. [email protected]
Numerous numbers of biologically active agents have been identified for their diverse therapeutic functions. Detailed investigations of phytochemicals for antiviral activities have assumed greater importance in the last few decades. A wide variety of active phytochemicals, including the flavonoids, terpenoids, organosulfur compounds, limonoids, lignans, sulphides, polyphenolics, coumarins, saponins, chlorophyllins, furyl compounds, alkaloids, polyines, thiophenes, proteins and peptides have been found to have therapeutic applications against different genetically and functionally diverse viruses. The antiviral mechanism of these agents may be explained on basis of their antioxidant activities, scavenging capacities, inhibiting DNA, RNA synthesis, inhibition of the viral entry, or inhibiting the viral reproduction etc. Large number candidate substances such as phytochemicals and their synthetic derivatives have been identified by a combination of in vitro and in vivo studies in different biological assays. In this article we have made attempts to extensively review and provide comprehensive description of different phyto-antiviral agents. We have examined the recent developments in the field of plant derived antiviral agents. The major advances in the field of viral interactions in various biological assays have been summarized. In addition sources of origin, major viral studies mechanistic action and phase trials of various phytoantiviral agents have been included in the review.
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Effects of a nutrient mixture on infectious properties of the highly pathogenic strain of avian influenza virus A/H5N1.
Deryabin PG, Lvov DK, Botikov AG, Ivanov V, Kalinovsky T, Niedzwiecki A, Rath M.
Source—Russian Academy of Medical Sciences, D.I. Ivanovsky Research Institute on Virology, USA.
Numerous outbreaks of avian influenza virus infection (A/H5N1) have occurred recently, infecting domestic birds, chicken and ducks. The possibility of the emergence of a new strain of influenza virus capable of causing a pandemic in humans is high and no vaccine effective against such a strain currently exists. A unique nutrient mixture (NM), containing lysine, proline, ascorbic acid, green tea extract, N-acetyl cysteine, selenium among other micro nutrients, has been shown to exert a wide range of biochemical and pharmacological effects, including an inhibitory effect on replication of influenza virus and HIV. This prompted us to investigate the potential anti-viral activity of a nutrient mixture (NM) and its components on avian influenza virus A/H5N1at viral dosages of 1.0, 0.1 and 0.01 TCID(50). Antiviral activity was studied in cultured cell lines PK, BHK-21, and Vero-E6. Virus lysing activity was determined by co-incubation of virus A/H5N1 with NM for 0-60 min, followed residual virulence titration in cultured SPEV or BHK-21 cells. NM demonstrated high antiviral activity evident even at prolonged periods after infection. NM antiviral properties were comparable to those of conventional drugs (amantadine and oseltamivir); however, NM had the advantage of affecting viral replication at the late stages of the infection process
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Nutrient mixture containing ascorbic acid, green tea extract and amino acids suppression of influenza A virus nuclear antigen production and neuraminidase activity by mixture
Jariwalla RJ, Roomi MW, Gangapurkar B, Kalinovsky T, Niedzwiecki A, Rath M.
Source–Dr. Rath Research Institute, Santa Clara, CA, USA.
Influenza, one of the oldest and most common infections, poses a serious health problem causing significant morbidity and mortality, and imposing substantial economic costs. The efficacy of current drugs is limited and improved therapies are needed. A unique nutrient mixture (NM), containing ascorbic acid, green tea extract, lysine, proline, N-acetyl cysteine, selenium among other micronutrients, has been shown to exert anti-carcinogenic and anti-atherogenic activity both in vitro and in vivo. Many of the constituents of NM have been shown to have an inhibitory effect on replication of influenza virus and HIV. This prompted us to study the effect of NM on influenza A virus multiplication in infected cells and neuraminidase activity (NA) in virus particles. Addition of NM to Vero or MDCK cells post infection resulted in dose-dependent inhibition of viral nucleoprotein (NP) production in infected cells. NM-mediated inhibition of viral NP was selective and not due to cytotoxicity towards host cells. This antiviral effect was enhanced by pretreatment of virus with the nutrient mixture. Individual components of NM, namely ascorbic acid and green tea extract, also blocked viral NP production, conferring enhanced inhibition when tested in combination. Incubation of cell-free virus with NM resulted in dose-dependent inhibition of associated NA enzyme activity. In conclusion, the nutrient mixture exerts an antiviral effect against influenza A virus by lowering viral protein production in infected cells and diminishing viral enzymatic activity in cell-free particles.
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Recipe Green Tea and Ascorbic acid—take gun powder green tea and weight out 20 grams and pulverize it to a powder—weigh it afterwards again—then take equal parts of ascorbic acid—1:1
Blend both together for about 5 minutes—then sift the stuff that did not break down—add to capsules and will have a strong antiviral and anti bacterial and antifungal remedy right on hand
[U1]How interesting —we have a GMM= genetically modified malaria—doe that not make you go hmmmmm wonder how it got genetically enhanced to resist what once cured it !!?—Is it not interesting that we have a new species of Malaria now—apparently the old one was not killing people off fast enough so now the pharma’ have decided to make this a better pathogen
[U2]WARNING WARNING—Understand this—Genetic Mutation–
[U3]Interesting—if they had the money they could be relieved but no money and they are held hostage by the IMF—what a crock
[U4] 90% kill ratio—-am I the only one seeing this is not a natural cause—weoponized malaria??