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Prebiotic May Help Patients With Intestinal Failure Grow New and Better Gut
ScienceDaily (Oct. 15, 2012) — Adding the right prebiotic to the diets of pediatric patients with intestinal failure could replace intravenous feeding, says a new University of Illinois study. “When we fed the carbohydrate fructooligosacharide (FOS) as a prebiotic, the gut grew and increased in function,” said Kelly A. Tappenden, a U of I professor of nutrition and gastrointestinal physiology. “The study showed that using the correct pre- and probiotic in combination could enhance these results even more.”–When FOS enters the intestines, bacteria convert it into butyrate, a short-chain fatty acid that increases the size of the gut and its ability to digest and absorb nutrients, she said[U2] .—But today’s IV solutions don’t contain butyrate and adding it would entail drug development trials and regulatory red tape. She wanted to see if adding this carbohydrate to the diet while continuing to provide most nutrients intravenously would cause the gut to start producing butyrate on its own. It worked According to Tappenden, at least 10,000 U.S. patients are totally reliant on intravenous feeding because their intestines have been surgically shortened. Many of these patients are premature infants who develop necrotizing enterocolitis, a kind of gangrene of the intestine. In the U.S., one in eight infants is a preemie, and removing necrotized, or dead, intestine is the most common surgical emergency in these babies. “Surgery saves their lives, but with so much intestine removed, they’re unable to digest or absorb nutrients. These babies are also at risk for long-term complications, such as bone demineralization and liver failure. Our goal is to take kids who’ve had this resection and cause their gut to grow and adapt,” she said.—She tested her hypothesis about butyrate using newborn piglets, an excellent model for the human infant in metabolism and physiology. Piglets with intestinal failure were assigned to one of four groups: a control group; a group whose diet contained FOS, a carbohydrate given as a prebiotic to stimulate the production of butyrate by beneficial bacteria; a probiotic, or actual live bacteria; and a combination of pre- and probiotics. -“We believed that bacteria in the gut would use the prebiotic to make butyrate and support intestinal growth. But we thought that might only happen in the group that received both pre- and probiotics because we didn’t know if the newborn gut would have enough bacteria to make this important short-chain fatty acid.” Actually, the neonatal piglets did have enough bacteria in their guts, and the prebiotic alone was effective in increasing intestinal function and structure, she said. “In fact, the probiotic that we used in one of the groups eliminated the beneficial effect of the prebiotic. That shows us that we need to be exceptionally careful in selecting the probiotic we use, matching it to the specific disease,” she noted. Many consumers believe all probiotics are equal, but the effect of specific bacterial strains is different, she said. “At this point, we can only recommend consumption of the FOS[U3] prebiotic alone,” she added.
The article appears in the September 2012 issue of the Journal of Parenteral and Enteral Nutrition. Jennifer L. Barnes of the U of I and Bolette Hartmann and Jens J. Holst of the University of Copenhagen, Copenhagen, Denmark, are co-authors of the study, which was funded by grants from the National Institutes of Health.—Journal References-J. L. Barnes, B. Hartmann, J. J. Holst, K. A. Tappenden. Intestinal Adaptation Is Stimulated by Partial Enteral Nutrition Supplemented With the Prebiotic Short-Chain Fructooligosaccharide in a Neonatal Intestinal Failure Piglet Model. Journal of Parenteral and Enteral Nutrition, 2012; 36 (5): 524 DOI: 10.1177/0148607112444131-K. A. Tappenden. Probiotics Are Not a One-Species-Fits-All Proposition. Journal of Parenteral and Enteral Nutrition, 2012; 36 (5): 496 DOI: 10.1177/0148607112458407
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Special Note as to why not to Consume grains— Amylose is the less easily digested component of Starch (only approximately 40% of dietary Amylose is digested via Amylase). Amylose that escapes digestion is known as Resistant Starch. Several factors influence the percentage of Amylose that escapes digestion— The physical structure of the Grain protects the starch from digestion (e.g. partly milled grains and pulses). The larger the Grain size, the higher the amount of Resistant Starch.
– The natural chemical composition of the starch in foods influences the amount of resistant starch. The higher the Amylose content of Starch, the greater its resistance to digestion. Raw Potato, green Bananas, pulses and high amylose Maize starch have a high Amylose content.—When Starch is heated, Starch granules swell and are disrupted. This process, known as gelatinisation, makes the Starch much more accessible to digestive enzymes. Starch with a high Amylose content and Starch which is inaccessible due to the physical structure in which it is located, are less susceptible to gelatinisation and hence are more resistant to digestion.
– When Starch that has been heated, is cooled, retrogradation occurs converting the Starch to a crystalline form which is resistant to digestion. Foods, such as bread, cornflakes, cold cooked potato, rice and pasta, contain retrograded starch which is resistant to digestion.
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Non Medical Prescription Drug Abuse-Substance Abuse From Doctors
Non-Medical Prescription Drug Use More Common Among Rural Teens Than City Dwellers
ScienceDaily (Nov. 2, 2010) — Rural teens appear more likely than their urban peers to use prescription drugs for non-medical purposes, according to a report posted online that will appear in the March 2011 print issue of Archives of Pediatrics & Adolescent Medicine, one of the JAMA/Archives journals.–The non-medical use of prescription drugs is common among U.S. adolescents, with about one in eight reporting lifetime non-medical use of prescription opioids, according to background information in the article. “During adolescence, non-medical prescription drug use is particularly problematic given its association with use of other illicit drugs such as cocaine and heroin, as well as engagement in problem behaviors such as gambling, increased sexual activity and impulsivity,” the authors write. “Moreover, individuals who use prescription drugs earlier in life have a greater chance of later developing prescription drug dependence[U4] .” Previous studies have examined substance abuse among urban teens, but their conclusions may not apply to those from rural areas, the authors note. Jennifer R. Havens, Ph.D., M.P.H., of University of Kentucky College of Medicine, Lexington, and colleagues analyzed data from 17,872 12- to 17-year-olds participating in the 2008 National Survey on Drug Use and Health. Of these, 53.2 percent lived in urban areas, 51 percent were male and 59 percent were white.—There were no differences between urban and rural youth in rates of any illicit drug use, including marijuana, cocaine, heroin and hallucinogens. However, 13 percent of rural teens reported ever having used prescription drugs for non-medical purposes, compared with 10 percent of urban teens. When the researchers assessed specific medication types, they found rural teens were also more likely to have used pain relievers (11.5 percent vs. 10.3 percent) or tranquilizers (3.5 percent vs. 2.5 percent) non-medically[U5] . –After adjusting for sociodemographic factors, health status and the use of other substances, rural teens remained 26 percent more likely than urban adolescents to say they had used prescription drugs for non-medical purposes. “Data support that one reason for the higher prevalence of non-medical prescription drug use in rural areas may be the lack of availability of drugs such as heroin that are easily accessed in urban areas,” the authors write.—Rural teens were more likely to misuse prescription drugs if they reported poorer health, episodes of depression or other substance abuse. “Residing in a household with two parents was associated with a 32 percent reduction in the odds of non-medical prescription drug use,” the[U6] authors write. “These results suggest that interventions aimed at family involvement may be beneficial in preventing or reducing non-medical prescription drug use.” Enrollment in school was also a protective factor.
“The cultural, structural and social realities of rural life can not only affect the prevalence of drug use but also exacerbate its consequences. The isolation and self-reliance of rural communities can negatively affect careseeking behavior, particularly regarding mental health and substance abuse services[U7] ,” the authors write. “While we were able to identify potential targets for intervention such as increased access to health, mental health and substance abuse treatment, this may be difficult for rural areas where such resources are in short supply or non-existent. Research into the causal mechanisms surrounding initiation of non-medical prescription drug use in rural adolescents is necessary to develop tailored interventions for this population.”–Story Source-The above story is reprinted from materials provided by JAMA and Archives Journals. —Journal Reference-Jennifer R. Havens; April M. Young; Christopher E. Havens. Nonmedical Prescription Drug Use in a Nationally Representative Sample of Adolescents: Evidence of Greater Use Among Rural Adolescents. Archives of Pediatrics & Adolescent Medicine, 2010; DOI: 10.1001/archpediatrics.2010.217
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Research Reveals Decline in Illicit Drug Abuse- Prescription Drug Abuse On the Rise
ScienceDaily (Oct. 15, 2012) — Research presented at the ANESTHESIOLOGY™ 2012 annual meeting showed while there has been an encouraging decline in illicit drug abuse across most major metropolitan areas in recent years, prescription drug abuse is climbing[U8] .–“Examining trends among various geographical areas, highlighting problem areas and possibly illuminating patterns that may remain otherwise hidden on a larger national level will help determine if we’ve stemmed the tide of prescription drug abuse or if a national epidemic has surfaced,” said study author Asokumar Buvanendran M.D., Rush University Medical Center and Professor, Department of Anesthesiology, Chicago.—About the Study—Emergency department drug abuse-related visits were extracted from the Drug Abuse Warning Network (DAWN) over three years (2007-09) for 11 major metropolitan areas (plus a combined “other” category of various smaller regions). Two types of drug abuse visits were examined; those associated with prescription drugs (e.g., pain medications such as OxyContin®) and those associated with illicit “street” drugs (e.g., heroin, cocaine, etc).—In 2007, the percentage of emergency department visits identifying the involvement of illicit drug abuse (36 percent) was consistently higher than prescription drug abuse (20 percent) for all metro areas except the Phoenix region. Among the metropolitan areas, rates of illicit drug abuse varied in magnitude considerably more than prescription drug abuse. Prescription drug abuse rates were more consistent across metropolitan areas but still displayed a few spikes, with higher rates in Houston (33 percent) and Phoenix (27 percent).
Change over time from 2007-09, for illicit drug abuse, showed a consistent downward trend for all metro areas (8 percent overall), while prescription drug abuse rates over this same time period changed much less, showing a slightly increasing trend (2 percent) with some areas increasing while others decrease.–Overall, in the U.S. the percentage of visits for illicit drug abuse decreased (2007: 36 percent, 2008: 32 percent, 2009: 28 percent) while prescription drug abuse visits increased (2007: 20 percent, 2008: 21 percent, 2009: 22 percent) and the total number of “visits” were: 2007: 301,000; 2008: 352,000; and 2009: 280,000.–“The harsh reality is prescription drug abuse has become a growing problem in our society,” said Dr. Buvanendran. “We hope the results of this study will aid physicians in effectively treating patients who struggle with prescription drug abuse, as well as encourage widespread patient education about the safe use, storage and disposal of medications.”—Story Source-The above story is reprinted from materials provided by American Society of Anesthesiologists (ASA), via Newswise.
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[U1]This is basically stating as well an over worked pancreas and liver—as a result of lack of sleep the other organs have to compensate for this excessive activity
[U2]Dietary Carbohydrates (especially Polysaccharides) are fermented (by Beneficial Bacteria) within the Large Intestine resulting in the manufacture of Butyric Acid: references
– Inulin may enhance the production of Butyric Acid in the Colon. references
– Of all Carbohydrates, Starch produces the greatest concentration of Butyric Acid: references
– The constituent of Starch that most contributes to the production of Butyric Acid is Amylose that escapes digestion (i.e. Resistant Starch). references
Fructooligosaccharides (FOS) (by nourishing Beneficial Bacteria in the Intestines which produce Butyric Acid) may facilitate the endogenous production of Butyric Acid in the digestive tract. references
Larch Arabinogalactan may stimulate the body’s production of Butyric Acid. references
Psyllium may increase the production of Butyric Acid in the Intestines (especially in the Colon). This effect occurs from Beneficial Bacteria in the Intestines fermenting Psyllium. references
Lipids
Acetic Acid may enhance the ability of Butyric Acid to stimulate the absorption of Calcium and Magnesium in the Colon. references
Beneficial Bacteria within the Large Intestine (especially the Colon) are responsible for the fermentation of dietary Carbohydrates that result in the production of Butyric Acid. references
Aspirin may enhances the ability of Butyric Acid to prevent Colon Cancer. references
Resveratrol may enhance the ability of Butyric Acid to prevent Colon Cancer. references
[U3]Chicory (root) Burdock
Vegetables: Leeks Onions
Tomatoes Garlic
Asparagus Jerusalem Artichoke
These foods will increase FOS
[U4]Now here’s a thought—what if in early infancy when Teachers working indirectly for the “State” tell you your offspring need a drug-ritalin—as you can see it will lead to an addictive state later on in life—or perhaps a Birth Control pill to offset pregnancy and then later on in life your taking HRT pills to regulate what was shut down
[U5]This research is splitting hairs here –what we have is a stressed or taxed group of people –in this case Caucasians who are looking at these prescriptions to alleviate whatever they are dealing with and it would appear the access is easier to gain in the rural areas–
[U6]In other words a specific level of security in regards not only to access but to the persons stability
[U7]Isolation and the issues of rural living usually are not the issue it is the access —the more connected a community is the less likely of this kind of behaviour—the less attached a person is or if there is any type of rejection or osterization then this may exacerbate the abuse
[U8]In other words No Real Decline at all –the access is now easier through Doctors
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Show Of The Week October 29 2012
GM Crops Destroyed by US Drought but non-GM Varieties Flourish
Contents of chemtrails jets have changed, it is now include plutonium
6-shogaol-rich extract from ginger up-regulates the antioxidant defense
Effect of dietary polyphenols on K562 leukemia cells- a Foodomics approach-Rosemary
50 Reasons to Oppose Fluoridation
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GM Crops Destroyed by US Drought but non-GM Varieties Flourish
Non-GM varieties are more drought resistant, yet agritech giants ensure farmers are unable to access them. Dr Eva Sirinathsinghji—-The United States is suffering the worst drought in 50 years. But crop damage may well have been avoided if high quality non-GM varieties were available to farmers. Further evidence is emerging that glyphosate-tolerant crops are ill- equipped to deal with drought, while high quality non-GM varieties are flourishing. Monopoly of the seed industry has left farmers unable to get non-GM varieties, despite the drought having global repercussions including steep rises of cereal prices and reduced meat production in many countries. In a commentary circulated by GM Watch (UK), Howard Vlieger, a co-founder and agroecological farming advisor of Verity Farms in drought-stricken South Dakota the US, provides evidence from a farmer who has grown both GM and Verity Farms’ non-GM varieties of soybean and corn side by side [1]. Non-GM soybean, grown in agroecological conditions to promote soil biodiversity and nutritional content is shown next to Monsanto’s GM triple-stack GM corn, which is glyphosate- tolerant and additionally expresses two Bt insecticidal toxins, grown using conventional chemical industrial methods that include the use of Monsanto’s glyphosate-based herbicide, Roundup (Figure 1). As captured in the photograph, non-GM varieties appear greener, fuller, and healthier. These impressions are backed up by the far superior yield reported of non-GM corn, which averaged 100- 120 bushels per acre (BPA) compared to the 8-12 BPA to 30-50 BPA of GM corn. -The large yield differential was confirmed in a new set of harvest data provided by Vlieger (with accompanying photographic identification) for three fields surrounding Verity Farm, all growing Smart Stack RR corn [2]. All were harvested for corn silage as the yields were too poor to harvest the grain. The federal crop insurance adjuster appraised yields were respectively 12 bushels per acre (BPA), 27 BPA, and 28 BPA. The Non-GMO corn on Verity Farm across the road yielded 108 BPA.—The findings were replicated with soybean crops
GM and non-GM soybean crops
Previous studies found glyphosate tolerant crops require more water– Triple Stack RR corn may be especially drought intolerant, but the new evidence
from the farm is consistent with previous laboratory findings that glyphosate- treated crops are less water efficient than untreated crops. One such study was performed in Brazil when farmers reported “injured-looking” glyphosate-tolerant soybean crops. The team, led by Luis Zobiole from State University of Maringá found that GM glyphosate-tolerant (GT) soybeans absorbed less water, which resulted in reduced water efficiency [3]. The volume of water that non-treated GT soybean plants required to produce 1 g of dry biomass was 204 % and 152 % less than required when the plant is exposed to 2 400 grams acid equivalent (a.e) of glyphosate per hectare, in single or sequential applications
respectively. GT soybean plants receiving a single application of the currently
recommended rates of glyphosate (600–1200 grams a.e per hectare) needed 13–20% more water to produce the same amount of dry biomass than non-glyphosate treated plants. A previous publication by the same lab showed GT soybeans to have reduced lignin content and photosynthesis rates, both possible mechanisms for the reduced water efficiency [4]. Lignin is an essential component of plant cell walls, and contributes to the compression strength of stems and to the efficient transport of water and solutes over long distances within the vascular system. Water deficiency is not the only physiological effect that glyphosate imposes on crops. It has been shown to reduce nutrient availability and immune responses and thus defence against plant diseases (see [5] Glyphosate Tolerant Crops Bring Death and Disease, SiS 47). At least 40 diseases are known to be increased in weed control programmes with glyphosate and the list is growing, affecting a wide range of species: apples, bananas, barley, bean, canola, citrus, cotton, grape, melon, soybean, sugar beet, sugarcane, tomato and wheat [6]. Monopolisation of the seed industry
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Contents of chemtrails jets have changed, it is now incl. plutonium
am hearing from all kind of friends who live in various parts of Europe that the contents from the Chemtrails what they used to spray on us has changed recently.
Some of my friends who have a Geiger counter are measuring INCREDIBLE high radiation quickly after those chemtrail planes flew over. This has never happened before that they measured radiation coming from the chemtrail jets a few minutes after they passed !! I have friends in FRANCE, UK, NETHERLANDS, GERMANY, SWITZERLAND. And they all measure these readings !!! This means that the globalist are misusing the situation from Japan and started to bombard the whole world with PLUTONIUM and[U1] such…. NOT BROUGHT BY THE WIND, BUT BY PLANES !!!!! Look at California I mean I just cannot believe that the Wind took this super high concentration of Radiation to this place. Also what I heard in the Netherlands, the radiation in the air is going sky high a few minutes after those chemtrail planes just did their spraying . So high that is almost comparable to measurements close to the area of Fukushima !!
IT IS NOT THE RADIATION COMING FROM JAPAN THAT IS INFECTING THE WORLD, IT IS THE RADIATION WHAT THEY ARE NOWADAYS DAILY LITERALLY SPRAYING ABOVE OUR HEADS. JUST LIKE WHAT THEY DID TO THE JEWS IN THE CAMPS !!! REMEMBER THOSE SHOWERS !!!!!!!!!
California:
http://blog.alexanderhiggins.com/2011/04/01/breaking-radiation-san-francisco-18100-drinking-water-limits-13014/
People who I see walking on the streets in my neighborhood are coughing like crazy over here (area in FRANCE)
Yesterday I helped an old woman to get up, she just dropped on the street, she forgot to take her rollator she told me. While she just had in her hand for god sake, it was laying next to her !!! But she did not realize it……
http://www.tennessean.com/article/20110316/NEWS08/110316027/1969/NEWS/Group-warns-EPA-ready-increase-radioactive-release-guidelines-?odyssey=nav|head
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6-shogaol-rich extract from ginger up-regulates the antioxidant defense systems in cells and mice.
Molecules. 2012;17(7):8037-55 Authors: Bak MJ, Ok S, Jun M, Jeong WS
Abstract—The rhizome of ginger (Zingiber officinale Roscoe) is known to have several bioactive compounds including gingerols and shogaols which possess beneficial health properties such as anti-inflammatory and chemopreventive effects. Based on recent observations that 6-shogaol may have more potent bioactivity than 6-gingerol, we obtained a 6-shogaol-rich extract from ginger and examined its effects on the nuclear factor E2-related factor2 (Nrf2)/antioxidant response element (ARE) pathway in vitro and in vivo. 6-Shogaol[U2] -rich extract was produced by extracting ginger powder with 95% ethanol at 80 °C after drying at 80 °C (GEE8080). GEE8080 contained over 6-fold more 6-shogaol compared to the room temperature extract (GEE80RT). In HepG2 cells, GEE8080 displayed much stronger inductions of ARE-reporter gene activity and Nrf2 expression than GEE80RT. GEE8080 stimulated phosphorylations of mitogen-activated protein kinases (MAPKs) such as ERK, JNK, and p38. Moreover, the GEE8080-induced expressions of Nrf2 and HO-1 were attenuated by treatments of SB202190 (a p38 specific inhibitor) and LY294002 (an Akt specific inhibitor). In a mouse model, the GEE8080 decreased the diethylnitrosamine (DEN)-mediated elevations of serum aspartate transaminase and alanine transaminase as well as the DEN-induced hepatic lipid peroxidation. Inductions of Nrf2 and HO-1 by GEE8080 were also confirmed in the mice. In addition, the administration of GEE8080 to the mice also restored the DEN-reduced activity and protein expression of hepatic antioxidant enzymes such as superoxide dismutase, glutathione peroxidase and catalase. In conclusion, GEE8080, a 6-shogaol-rich ginger extract, may enhance antioxidant defense mechanism through the induction of Nrf2 and HO-1 regulated by p38 MAPK and PI3k/Akt pathway in vitro and in vivo.—PMID: 22763741 [PubMed – indexed for MEDLINE]—
Recipe for ginger antioxidant -shogoal—either dehydrate ginger or buy the powder and add it to a alcohol base—if in the USA use ever clear—In Canada depending where you live utilize the polish version of everclear orr get a home made grappa—or buy a 90 proof if you can locate ( Canada has differering laws from province to province unfortunately in Ontario the gov’t still feels the need to control the dose of alcohol and access)—what you would do is take this and extract it in the alcohol medium by utilizing a mason jar and the bottom of a blender attachment—seal the jar with a tape and then place the powder and alcohol inside and then twist the bottom of the jar and seal it and proceed to blend this at medium to high speed—for 10-15 minutes then stop the blender and strain off the powder ginger—be careful this will be hot—this will give you this in it’s antioxidant levels at the rate they are explaining—if you cannot access the high alcohol then use the 40 or 50 proof it will still work but maybe 3 times stronger rather then 6 times
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Effect of dietary polyphenols on K562 leukemia cells- a Foodomics approach-Rosemary
Electrophoresis. 2012 Aug;33(15):2314-27
Authors: Valdés A, Simó C, Ibáñez C, Rocamora-Reverte L, Ferragut JA, García-Cañas V, Cifuentes A
Abstract– this work, a global Foodomics strategy has been applied to study the antiproliferative effect of dietary polyphenols from rosemary on two human leukemia lines, one showing a drug-sensitive phenotype (K562), and another exhibiting a drug-resistant phenotype (K562/R). To this aim, whole-transcriptome microarray together with an MS-based nontargeted analytical approach (via CE-TOF MS and UPLC-TOF MS) have been employed to carry out transcriptomics and metabolomics analyses, respectively. Functional enrichment analysis was done using ingenuity pathway analysis (IPA) software as a previous step for a reliable interpretation of transcriptomic and metabolomic profiles. Rosemary polyphenols altered the expression of approximately 1% of the genes covered by the whole transcriptome microarray in both leukemia cell lines. Overall, differences in the transcriptional induction of a number of genes encoding phase II detoxifying and antioxidant genes, as well as differences in the metabolic profiles observed in the two leukemia cell lines suggest that rosemary polyphenols may exert a differential chemopreventive effect in leukemia cells with different phenotypes. IPA predictions on transcription factor analysis highlighted inhibition of Myc transcription factor function by rosemary polyphenols, which may explain the observed antiproliferative effect of rosemary extract in the leukemia cells. Metabolomics analysis suggested that rosemary polyphenols affected differently the intracellular levels of some metabolites in two leukemia cell sublines. Integration of data obtained from transcriptomics and metabolomics platforms was attempted by overlaying datasets on canonical (defined) metabolic pathways using IPA software. This strategy enabled the identification of several differentially expressed genes in the metabolic pathways modulated by rosemary polyphenols providing more evidences on the effect of these compounds.—PMID: 22887152 [PubMed – indexed for MEDLINE]
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[U1]I stated about a year ago that the chemtrails maybe different in different areas—it would appear I am right and with the newest dumping on the planet it will be used to heat and cause environmental imbalances we are see today
[U2]Shogaol is a antioxidant that comes from the dehydrated part of the ginger—gingerol comes from the fresh part this can be made with both but in this case they are explaining how to make this with the dry form